Publications

Recent Publications

2023 September

Distinct pathways of adaptive evolution in Cryptococcus neoformans reveal a mutation in adenylyl cyclase with trade-offs for pathogenicity. Hilbert ZA, Bednarek JM, Schwiesow MJW, Chung KY, Moreau CT, Brown JCS, Elde NC.Curr Biol. 2023 Sep 8:S0960-9822(23)01134-X. doi: 10.1016/j.cub.2023.08.054. Online ahead of print.PMID: 37708888

The transcriptomic landscape of normal and ineffective erythropoiesis at single-cell resolution. Doty RT, Lausted CG, Munday AD, Yang Z, Yan X, Meng C, Tian Q, Abkowitz JL.Blood Adv. 2023 Sep 12;7(17):4848-4868. doi: 10.1182/bloodadvances.2023010382.PMID: 37352261

Platelet mitochondria: the mighty few. Ajanel A, Campbell RA, Denorme F.Curr Opin Hematol. 2023 Sep 1;30(5):167-174. doi: 10.1097/MOH.0000000000000772. Epub 2023 Jul 17.PMID: 37459354

The predominant PAR4 variant in individuals of African ancestry worsens murine and human stroke outcomes. Denorme F, Armstrong ND, Stoller ML, Portier I, Tugolukova EA, Tanner RM, Montenont E, Bhatlekar S, Cody M, Rustad JL, Ajanel A, Tolley ND, Murray DC, Boyle JL, Nieman MT, McKenzie SE, Yost CC, Lange LA, Cushman M, Irvin MR, Bray PF, Campbell RA.J Clin Invest. 2023 Sep 15;133(18):e169608. doi: 10.1172/JCI169608.PMID: 37471144

Animal FAS-like polyketide synthases produce diverse polypropionates. Li F, Lin Z, Krug PJ, Catrow JL, Cox JE, Schmidt EW.Proc Natl Acad Sci U S A. 2023 Sep 19;120(38):e2305575120. doi: 10.1073/pnas.2305575120. Epub 2023 Sep 11.PMID: 37695909

 

2023 August

Microbe transmission from pet shop to lab-reared zebrafish reveals a pathogenic birnavirus. Rice MC, Elde NC, Gagnon JA, Balla KM.bioRxiv. 2023 Aug 28:2023.08.28.555169. doi: 10.1101/2023.08.28.555169. Preprint.PMID: 37693489 Free PMC article.

Structural homology screens reveal host-derived poxvirus protein families impacting inflammasome activity. Boys IN, Johnson AG, Quinlan MR, Kranzusch PJ, Elde NC.Cell Rep. 2023 Aug 29;42(8):112878. doi: 10.1016/j.celrep.2023.112878. Epub 2023 Jul 25.PMID: 37494187

Acute activation of adipocyte lipolysis reveals dynamic lipid remodeling of the hepatic lipidome. Zhang S, Williams KJ, Verlande-Ferrero A, Chan AP, Su GB, Kershaw EE, Cox JE, Maschek JA, Shapira SN, Christofk HR, de Aguiar Vallim TQ, Masri S, Villanueva CJ.J Lipid Res. 2023 Aug 26:100434. doi: 10.1016/j.jlr.2023.100434. Online ahead of print.PMID: 37640283

Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease. Ocañas SR, Pham KD, Cox JE, Keck AW, Ko S, Ampadu FA, Porter HL, Ansere VA, Kulpa A, Kellogg CM, Machalinski AH, Thomas MA, Wright Z, Chucair-Elliott AJ, Freeman WM.J Neuroinflammation. 2023 Aug 16;20(1):188. doi: 10.1186/s12974-023-02870-2.PMID: 37587511 Free PMC article.

Feasibility of a non-invasive method to assess fetal hemolysis in utero during the third trimester. Bahr TM, Christensen TR, Cheatham LS, Page JM, Christensen RD.J Perinatol. 2023 Aug 31. doi: 10.1038/s41372-023-01764-8. Online ahead of print.PMID: 37653077 No abstract available.

Serum ferritin values in neonates <29 weeks’ gestation are highly variable and do not correlate with reticulocyte hemoglobin content. Bahr TM, Tan S, Smith E, Beauman SS, Schibler KR, Grisby CA, Lowe JR, Bell EF, Laptook AR, Shankaran S, Carlton DP, Rau C, Baserga MC, Flibotte J, Zaterka-Baxter K, Walsh MC, Das A, Christensen RD, Ohls RK; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network.J Perinatol. 2023 Aug 18. doi: 10.1038/s41372-023-01751-z. Online ahead of print.PMID: 37596391

Neonatal Thrombocytopenia: Factors Associated With the Platelet Count Increment Following Platelet Transfusion. Christensen RD, Bahr TM, Davenport P, Sola-Visner MC, Kelley WE, Ilstrup SJ, Ohls RK.J Pediatr. 2023 Aug 11;263:113666. doi: 10.1016/j.jpeds.2023.113666. Online ahead of print.PMID: 37572863

Lactate modulates iron metabolism by binding soluble adenylyl cyclase. Liu W, Zhang S, Li Q, Wu Y, Jia X, Feng W, Li Z, Shi Y, Hou Q, Ma J, Liu Y, Gao P, Ganz T, Liu S.Cell Metab. 2023 Sep 5;35(9):1597-1612.e6. doi: 10.1016/j.cmet.2023.06.017. Epub 2023 Jul 21.PMID: 37480842

Increased transferrin protects from thrombosis in Chuvash erythrocytosis. Shah BN, Zhang X, Sergueeva AI, Miasnikova GY, Ganz T, Prchal JT, Gordeuk VR.Am J Hematol. 2023 Oct;98(10):1532-1539. doi: 10.1002/ajh.27021. Epub 2023 Jul 12.PMID: 37435906

Increased blood reactive oxygen species and hepcidin in obstructive sleep apnea precludes expected erythrocytosis.

Song J, Sundar KM, Horvathova M, Gangaraju R, Indrak K, Christensen RD, Genzor S, Lundby C, Divoky V, Ganz T, Prchal JT.Am J Hematol. 2023 Aug;98(8):1265-1276. doi: 10.1002/ajh.26992. Epub 2023 Jun 23.PMID: 37350302

Iron Homeostasis During Pregnancy: Maternal, Placental, and Fetal Regulatory Mechanisms. Sangkhae V, Fisher AL, Ganz T, Nemeth E.Annu Rev Nutr. 2023 Aug 21;43:279-300. doi: 10.1146/annurev-nutr-061021-030404. Epub 2023 May 30.PMID: 37253681

Evidence that the catalytic mechanism of heme a synthase involves the formation of a carbocation stabilized by a conserved glutamate. Rivett ED, Addis HG, Dietz JV, Carroll-Deaton JA, Gupta S, Foreman KL, Dang MA, Fox JL, Khalimonchuk O, Hegg EL.Arch Biochem Biophys. 2023 Aug;744:109665. doi: 10.1016/j.abb.2023.109665. Epub 2023 Jun 20.PMID: 37348627

The complex relationship between iron status and anemia in pregnant and postpartum women in India: Analysis of two Indian study cohorts of uncomplicated pregnancies. Nair M, Choudhury SS, Rani A, Solomi C 5th, Kakoty SD, Medhi R, Rao S, Mahanta P, Zahir F, Roy I, Chhabra S, Deka G, Minz B, Deka R, Opondo C, Churchill D, Lakhal-Littleton S, Nemeth E; MaatHRI collaboration.Am J Hematol. 2023 Aug 31. doi: 10.1002/ajh.27059. Online ahead of print.PMID: 37651649

The iron chaperone poly C binding protein 1 regulates iron efflux through intestinal ferroportin in mice. Wang Y, Protchenko O, Duck Huber K, Shakoury-Elizeh M, Ghosh MC, Philpott CC.Blood. 2023 Aug 25:blood.2023020504. doi: 10.1182/blood.2023020504. Online ahead of print.PMID: 37624904

Cardiac gene therapy rescues diabetic cardiomyopathy and lowers blood glucose. Li J, Richmond B, Cluntun AA, Bia R, Walsh MA, Shaw K, Symons JD, Franklin S, Rutter J, Funai K, Shaw RM, Hong T.JCI Insight. 2023 Aug 24:e166713. doi: 10.1172/jci.insight.166713. Online ahead of print.PMID: 37639557

Who is pregnant? Defining real-world data-based pregnancy episodes in the National COVID Cohort Collaborative (N3C). Jones SE, Bradwell KR, Chan LE, McMurry JA, Olson-Chen C, Tarleton J, Wilkins KJ, Ly V, Ljazouli S, Qin Q, Faherty EG, Lau YK, Xie C, Kao YH, Liebman MN, Mariona F, Challa AP, Li L, Ratcliffe SJ, Haendel MA, Patel RC, Hill EL; N3C Consortium.JAMIA Open. 2023 Aug 16;6(3):ooad067. doi: 10.1093/jamiaopen/ooad067. eCollection 2023 Oct.PMID: 37600074

Ceramides Increase Fatty Acid Utilization in Intestinal Progenitors to Enhance Stemness and Increase Tumor Risk. Li Y, Chaurasia B, Rahman MM, Kaddai V, Maschek JA, Berg JA, Wilkerson JL, Mahmassani ZS, Cox J, Wei P, Meikle PJ, Atkinson D, Wang L, Poss AM, Playdon MC, Tippetts TS, Mousa EM, Nittayaboon K, Babu PVA, Drummond MJ, Clevers H, Shayman JA, Hirabayashi Y, Holland WL, Rutter J, Edgar B, Summers SA.Gastroenterology. 2023 Aug 2:S0016-5085(23)04837-0. doi: 10.1053/j.gastro.2023.07.017. Online ahead of print.PMID: 37541526

UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability. Tsai JM, Aguirre JD, Li YD, Brown J, Focht V, Kater L, Kempf G, Sandoval B, Schmitt S, Rutter JC, Galli P, Sandate CR, Cutler JA, Zou C, Donovan KA, Lumpkin RJ, Cavadini S, Park PMC, Sievers Q, Hatton C, Ener E, Regalado BD, Sperling MT, Słabicki M, Kim J, Zon R, Zhang Z, Miller PG, Belizaire R, Sperling AS, Fischer ES, Irizarry R, Armstrong SA, Thomä NH, Ebert BL.Mol Cell. 2023 Aug 3;83(15):2753-2767.e10. doi: 10.1016/j.molcel.2023.06.028. Epub 2023 Jul 20.PMID: 37478846

Oct4 redox sensitivity potentiates reprogramming and differentiation. Shen Z, Wu Y, Manna A, Evason KJ, Chandrasekharan MB, Tantin D.bioRxiv. 2023 Aug 24:2023.02.21.529404. doi: 10.1101/2023.02.21.529404. Preprint.PMID: 36865286

 

2023 July

The impact of prenatal inflammation on hematopoietic development. Tseng NA, Beaudin AE.Curr Opin Hematol. 2023 Jul 1;30(4):130-136. doi: 10.1097/MOH.0000000000000770. Epub 2023 May 9.PMID: 37254855

A zebrafish model of combined saposin deficiency identifies acid sphingomyelinase as a potential therapeutic target. Zhang T, Alonzo I, Stubben C, Geng Y, Herdman C, Chandler N, Doane KP, Pluimer BR, Trauger SA, Peterson RT.Dis Model Mech. 2023 Jul 1;16(7):dmm049995. doi: 10.1242/dmm.049995. Epub 2023 Jun 27.PMID: 37183607

Mon1a and FCHO2 are required for maintenance of Golgi architecture. Bagley DC, Morham SG, Kaplan J, Ward DM.bioRxiv. 2023 Jul 7:2023.07.06.547837. doi: 10.1101/2023.07.06.547837. Preprint.PMID: 37461455

Loss of the mitochondrial protein Abcb10 results in altered arginine metabolism in MEL and K562 cells and nutrient stress signaling through ATF4. Miljkovic M, Seguin A, Jia X, Cox JE, Catrow JL, Bergonia H, Phillips JD, Stephens WZ, Ward DM.J Biol Chem. 2023 Jul;299(7):104877. doi: 10.1016/j.jbc.2023.104877. Epub 2023 Jun 1.PMID: 37269954

Disuse-induced muscle fibrosis, cellular senescence, and senescence-associated secretory phenotype in older adults are alleviated during re-ambulation with metformin pre-treatment. Petrocelli JJ, McKenzie AI, de Hart NMMP, Reidy PT, Mahmassani ZS, Keeble AR, Kaput KL, Wahl MP, Rondina MT, Marcus RL, Welt CK, Holland WL, Funai K, Fry CS, Drummond MJ.Aging Cell. 2023 Jul 24:e13936. doi: 10.1111/acel.13936. Online ahead of print.PMID: 37486024

Actin-bundling protein L-plastin promotes megakaryocyte rigidity and dampens proplatelet formation. Guo L, Jacob S, Manne BK, Kolawole EM, Guo S, Wang X, Murray D, Tugolukova EA, Portier I, Kosaka Y, Barba C, Rondina MT, Evavold B, Morley C, Bhatlekar S, Bray PF.Haematologica. 2023 Jul 13. doi: 10.3324/haematol.2023.283016. Online ahead of print.PMID: 37439340

Notes from the Underground: Heme Homeostasis in C. elegans. Chen C, Hamza I.Biomolecules. 2023 Jul 19;13(7):1149. doi: 10.3390/biom13071149.PMID: 37509184

Mitochondrial-Derived Compartments are Multilamellar Domains that Encase Membrane Cargo and Cytosol. Wilson ZN, West M, English AM, Odorizzi G, Hughes AL.bioRxiv. 2023 Jul 7:2023.07.07.548169. doi: 10.1101/2023.07.07.548169. Preprint.PMID: 37461645

Placental Erythroferrone and Erythropoietin mRNA Expression is not Associated with Maternal or Neonatal Iron Status in Adolescents Carrying Singletons and Adult Women Carrying Multiples. Delaney KM, Barad A, Castillo LF, Hasund CM, Guillet R, Pressman EK, Katzman PJ, Ganz T, Nemeth E, O’Brien KO.J Nutr. 2023 Jul;153(7):1950-1958. doi: 10.1016/j.tjnut.2023.05.023. Epub 2023 May 28.PMID: 37253412

Inhibition of skeletal muscle Lands cycle ameliorates weakness induced by physical inactivity. Shahtout JL, Eshima H, Ferrara PJ, Maschek JA, Cox JE, Drummond MJ, Funai K.bioRxiv. 2023 Jul 28:2023.07.25.550576. doi: 10.1101/2023.07.25.550576. Preprint.PMID: 37546754

Rapid Evolution of Glycan Recognition Receptors Reveals an Axis of Host-Microbe Arms Races beyond Canonical Protein-Protein Interfaces. Hilbert ZA, Haffener PE, Young HJ, Schwiesow MJW, Leffler EM, Elde NC.Genome Biol Evol. 2023 Jul 3;15(7):evad119. doi: 10.1093/gbe/evad119.PMID: 37390614

Concurrent profiling of multiscale 3D genome organization and gene expression in single mammalian cells. Zhou T, Zhang R, Jia D, Doty RT, Munday AD, Gao D, Xin L, Abkowitz JL, Duan Z, Ma J.bioRxiv. 2023 Jul 25:2023.07.20.549578. doi: 10.1101/2023.07.20.549578. Preprint.PMID: 37546900

BMP5 contributes to hepcidin regulation and systemic iron homeostasis in mice. Xiao X, Xu Y, Moschetta GA, Yu Y, Fisher AL, Alfaro-Magallanes VM, McMillen S, Phillips S, Wang CY, Christian JBabitt JL.Blood. 2023 Jul 21:blood.2022019195. doi: 10.1182/blood.2022019195. Online ahead of print.PMID: 37478395

Both maternal IFNγ exposure and acute prenatal infection with Toxoplasma gondii activate fetal hematopoietic stem cells. López DA, Otsuka KS, Apostol AC, Posada J, Sánchez-Arcila JC, Jensen KD, Beaudin AE. EMBO J. 2023 Jul 17;42(14):e112693. doi: 10.15252/embj.2022112693. Epub 2023 Jun 1.PMID: 37259639

Renin-Angiotensin System Components and Arachidonic Acid Metabolites as Biomarkers of COVID-19. Ghimire B, Pour SK, Middleton E, Campbell RA, Nies MA, Aghazadeh-Habashi A.Biomedicines. 2023 Jul 27;11(8):2118. doi: 10.3390/biomedicines11082118.PMID: 37626615

Role of Anemia in Dementia Risk Among Veterans With Incident CKD. Koyama AK, Nee R, Yu W, Choudhury D, Heng F, Cheung AK, Norris KC, Cho ME, Yan G.Am J Kidney Dis. 2023 Jul 27:S0272-6386(23)00735-7. doi: 10.1053/j.ajkd.2023.04.013. Online ahead of print.PMID: 37516301

A “Gold Standard” Test for Diagnosing and Quantifying Hemolysis in Neonates and Infants. Christensen RD, Bahr TM, Wong RJ, Vreman HJ, Bhutani VK, Stevenson DK.J Perinatol. 2023 Jul 19. doi: 10.1038/s41372-023-01730-4. Online ahead of print.PMID: 37468612 Review.

Associations between blood donor sex and age, and outcomes of transfused newborn infants. Bahr TM, Christensen TR, Tweddell SM, Henry E, Rees T, Astin ME, Kelley WE, Ilstrup SJ, Ohls RK, Christensen RD.Transfusion. 2023 Jul;63(7):1290-1297. doi: 10.1111/trf.17417. Epub 2023 May 22.PMID: 37218104

 

2023 June

Iron Parameters in Patients Treated with Roxadustat for Anemia of Chronic Kidney Disease. Ganz T, Locatelli F, Arici M, Akizawa T, Reusch M.J Clin Med. 2023 Jun 22;12(13):4217. doi: 10.3390/jcm12134217.PMID: 37445252

Diagnosing Anemia in Neonates: An Evidence-Based Approach. Christensen RD, Bahr TM, Tweddell SM, Ohls RK, Henry E.Neoreviews. 2023 Jun 1;24(6):e343-e355. doi: 10.1542/neo.24-6-e343.PMID: 37258503 Review.

Large-scale F0 CRISPR screens in vivo using MIC-Drop. Parvez S, Brandt ZJ, Peterson RT. Nat Protoc. 2023 Jun;18(6):1841-1865. doi: 10.1038/s41596-023-00821-y. Epub 2023 Apr 17.PMID: 3706931

Not All Heme is “Free” in Sickle Cell Disease. Vinchi F.Hemasphere. 2023 Jun 19;7(7):e910. doi: 10.1097/HS9.0000000000000910. eCollection 2023 Jul.PMID: 37346451

On either side of homeostasis: EPAS1 gain and loss of function mutations. Prchal JT, Semenza GL.Haematologica. 2023 Jun 8. doi: 10.3324/haematol.2023.283285. Online ahead of print.PMID: 37288511


Identification of Genomic Loci Regulating Platelet Plasminogen Activator Inhibitor-1 in Mice.
Siebert AE, Brake MA, Verbeek SC, Johnston AJ, Morgan AP, Cleuren AC, Jurek AM, Schneider CD, Germain DM, Battistuzzi FU, Zhu G, Miller DR, Johnsen JM, Pardo-Manuel de Villena F, Rondina MT, Westrick RJ.J Thromb Haemost. 2023 Jun 24:S1538-7836(23)00503-2. doi: 10.1016/j.jtha.2023.06.018. Online ahead of print.PMID: 37364776

Biomarkers of erythropoiesis response to intravenous iron in a crossover pilot study in unexplained anemia of the elderly. Yoo JJ, Cohen HJ, Artz AS, Price E, Fill JA, Prchal J, Sapp S, Barnhart H; from the Partnership for Anemia Clinical and Translational Trials in the Elderly (PACTTE).Hematology. 2023 Dec;28(1):1-8. doi: 10.1080/16078454.2023.2204613.PMID: 37114660

Impact of Cryopreservation on Extracorporeal Photopheresis (ECP)-Treated Leukocyte Subsets. Trunk AD, Radwanski K, Heber C, Taylor A, Hsieh F, Harris A, Lee CJ, Phillips JD, Couriel DR.Transplant Cell Ther. 2023 Jun;29(6):396.e1-396.e5. doi: 10.1016/j.jtct.2023.02.017. Epub 2023 Feb 23.PMID: 36828177

Evidence that the catalytic mechanism of heme a synthase involves the formation of a carbocation stabilized by a conserved glutamate. Rivett ED, Addis HG, Dietz JV, Carroll-Deaton JA, Gupta S, Foreman KL, Dang MA, Fox JL, Khalimonchuk O, Hegg EL.Arch Biochem Biophys. 2023 Jun 20:109665. doi: 10.1016/j.abb.2023.109665. Online ahead of print.PMID: 37348627

RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia. Ren JG, Xing B, Lv K, O’Keefe RA, Wu M, Wang R, Bauer KM, Ghazaryan A, Burslem GM, Zhang J, O’Connell RM, Pillai V, Hexner EO, Philips MR, Tong W.J Clin Invest. 2023 Jun 15;133(12):e165510. doi: 10.1172/JCI165510.PMID: 37317963

7TSG6 hyaluronan matrix remodeling dampens the inflammatory response during colitis. Albtoush N, Queisser KA, Zawerton A, Lauer ME, Beswick EJ, Petrey AC.Matrix Biol. 2023 Jun 28:S0945-053X(23)00077-X. doi: 10.1016/j.matbio.2023.06.007. Online ahead of print.PMID: 37391162

Estrogen receptor alpha mutations regulate gene expression and cell growth in breast cancer through microRNAs. Arnesen S, Polaski JT, Blanchard Z, Osborne KS, Welm AL, O’Connell RM, Gertz J.NAR Cancer. 2023 Jun 1;5(2):zcad027. doi: 10.1093/narcan/zcad027. eCollection 2023 Jun.PMID: 37275275

Pyruvate metabolism controls chromatin remodeling during CD4+ T cell activation. Mocholi E, Russo L, Gopal K, Ramstead AG, Hochrein SM, Vos HR, Geeven G, Adegoke AO, Hoekstra A, van Es RM, Pittol JR, Vastert S, Rutter J, Radstake T, van Loosdregt J, Berkers C, Mokry M, Anderson CC, O’Connell RM, Vaeth M, Ussher J, Burgering BMT, Coffer PJ.Cell Rep. 2023 Jun 1;42(6):112583. doi: 10.1016/j.celrep.2023.112583. Online ahead of print.PMID: 37267106

Hypoferremia of inflammation: Innate host defense against infections. Ganz T, Nemeth E.Blood Cells Mol Dis. 2023 Jun 21:102777. doi: 10.1016/j.bcmd.2023.102777. Online ahead of print.PMID: 37391347

In Vitro Generation of Murine Dendritic Cells from Hoxb8-Immortalized Hematopoietic Progenitors. Häcker H.Methods Mol Biol. 2023;2618:93-107. doi: 10.1007/978-1-0716-2938-3_7.PMID: 36905511

Macrophage metabolic rewiring improves heme-suppressed efferocytosis and tissue damage in sickle cell disease. Sharma R, Antypiuk A, Vance SZ, Manwani D, Pearce Q, Cox JE, An X, Yazdanbakhsh K, Vinchi F.Blood. 2023 Jun 22;141(25):3091-3108. doi: 10.1182/blood.2022018026.PMID: 36952641

Diagnosing Anemia in Neonates: An Evidence-Based Approach. Christensen RD, Bahr TM, Tweddell SM, Ohls RK, Henry E.Neoreviews. 2023 Jun 1;24(6):e343-e355. doi: 10.1542/neo.24-6-e343.PMID: 37258503

The transcriptomic landscape of normal and ineffective erythropoiesis at single-cell resolution. Doty RT, Lausted CG, Munday AD, Yang Z, Yan X, Meng C, Tian Q, Abkowitz JL.Blood Adv. 2023 Jun 23:bloodadvances.2023010382. doi: 10.1182/bloodadvances.2023010382. Online ahead of print.PMID: 37352261

Rapid evolution of glycan recognition receptors reveals an axis of host-microbe arms races beyond canonical protein-protein interfaces. Hilbert ZA, Haffener PE, Young HJ, Schwiesow MJW, Leffler EM, Elde NC.Genome Biol Evol. 2023 Jun 30:evad119. doi: 10.1093/gbe/evad119. Online ahead of print.PMID: 37390614

Phase 1/2 Study of Sorafenib Added to Cladribine, High-Dose Cytarabine, G-CSF, and Mitoxantrone in Untreated AML. Halpern AB, Rodríguez-Arbolí E, Othus M, Garcia KA, Percival MM, Cassaday RD, Oehler VG, Becker PS, Appelbaum J, Abkowitz JL, Orozco JJ, Keel SB, Hendrie P, Scott BL, Ghiuzeli CMM, Estey E, Walter RB.Blood Adv. 2023 Jun 20:bloodadvances.2023010392. doi: 10.1182/bloodadvances.2023010392. Online ahead of print.PMID: 37339483

Both maternal IFNγ exposure and acute prenatal infection with Toxoplasma gondii activate fetal hematopoietic stem cells. López DA, Otsuka KS, Apostol AC, Posada J, Sánchez-Arcila JC, Jensen KD, Beaudin AE.EMBO J. 2023 Jun 1:e112693. doi: 10.15252/embj.2022112693. Online ahead of print.PMID: 37259639

Increased blood reactive oxygen species and hepcidin in obstructive sleep apnea precludes expected erythrocytosis. Song J, Sundar KM, Horvathova M, Gangaraju R, Indrak K, Christensen RD, Genzor S, Lundby C, Divoky V, Ganz T, Prchal JT.Am J Hematol. 2023 Jun 23. doi: 10.1002/ajh.26992. Online ahead of print.PMID: 37350302

Platelet Transfusions in a Multi-Neonatal Intensive Care Unit Health Care Organization Before and After Publication of the PlaNeT-2 Clinical Trial. Bahr TM, Christensen TR, Henry E, Astin M, Ilstrup SJ, Ohls RK, Christensen RD.J Pediatr. 2023 Jun;257:113388. doi: 10.1016/j.jpeds.2023.03.003. Epub 2023 Mar 16.PMID: 36933765

Placental abruption and neonatal anemia. Tweddell SM, Bahr TM, Henry E, Page JM, Ilstrup SJ, Ohls RK, Christensen RD.J Perinatol. 2023 Jun;43(6):782-786. doi: 10.1038/s41372-023-01603-w. Epub 2023 Jan 17.PMID: 36650233

Lack of evidence that fibrillin1 regulates bone morphogenetic protein 4 activity in kidney or lung. McKnite A, Kim HS, Silva J, Christian JL.Dev Dyn. 2023 Jun;252(6):761-769. doi: 10.1002/dvdy.578. Epub 2023 Mar 6.PMID: 36825302

Loss of the mitochondrial protein Abcb10 results in altered arginine metabolism in MEL and K562 cells and nutrient stress signaling through ATF4. Miljkovic M, Seguin A, Jia X, Cox JE, Catrow JL, Bergonia H, Phillips JD, Stephens WZ, Ward DM.J Biol Chem. 2023 Jun 1;299(7):104877. doi: 10.1016/j.jbc.2023.104877. Online ahead of print.PMID: 37269954

An early, reversible cholesterolgenic etiology of diet-induced insulin resistance. Covert JD, Grice BA, Thornburg MG, Kaur M, Ryan AP, Tackett L, Bhamidipati T, Stull ND, Kim T, Habegger KM, McClain DA, Brozinick JT, Elmendorf JS.Mol Metab. 2023 Jun;72:101715. doi: 10.1016/j.molmet.2023.101715. Epub 2023 Apr 3.PMID: 37019209

 

2023 May

Novel anemia therapies in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Ku E, Del Vecchio L, Eckardt KU, Haase VH, Johansen KL, Nangaku M, Tangri N, Waikar SS, Więcek A, Cheung M, Jadoul M, Winkelmayer WC, Wheeler DC, Babitt JL; for Conference Participants.Kidney Int. 2023 May 24:S0085-2538(23)00379-4. doi: 10.1016/j.kint.2023.05.009. Online ahead of print.PMID: 37236424

The transcriptional and regulatory identity of erythropoietin producing cells. Kragesteen BK, Giladi A, David E, Halevi S, Geirsdóttir L, Lempke OM, Li B, Bapst AM, Xie K, Katzenelenbogen Y, Dahl SL, Sheban F, Gurevich-Shapiro A, Zada M, Phan TS, Avellino R, Wang SY, Barboy O, Shlomi-Loubaton S, Winning S, Markwerth PP, Dekalo S, Keren-Shaul H, Kedmi M, Sikora M, Fandrey J, Korneliussen TS, Prchal JT, Rosenzweig B, Yutkin V, Racimo F, Willerslev E, Gur C, Wenger RH, Amit I.Nat Med. 2023 May;29(5):1191-1200. doi: 10.1038/s41591-023-02314-7. Epub 2023 Apr 27.PMID: 37106166


Direct tests of cytochrome c and c1 functions in the electron transport chain of malaria parasites.
Espino-Sanchez TJ, Wienkers H, Marvin RG, Nalder SA, García-Guerrero AE, VanNatta PE, Jami-Alahmadi Y, Mixon Blackwell A, Whitby FG, Wohlschlegel JA, Kieber-Emmons MT, Hill CP, Sigala PA.Proc Natl Acad Sci U S A. 2023 May 9;120(19):e2301047120. doi: 10.1073/pnas.2301047120. Epub 2023 May 1.PMID: 37126705

The secret life of lactate: A novel cell-cycle regulatory mechanism. Cluntun AA, Rutter J.Cell Metab. 2023 May 2;35(5):730-732. doi: 10.1016/j.cmet.2023.04.006.PMID: 37137286

FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity. Wieder N, Fried JC, Kim C, Sidhom EH, Brown MR, Marshall JL, Arevalo C, Dvela-Levitt M, Kost-Alimova M, Sieber J, Gabriel KR, Pacheco J, Clish C, Abbasi HS, Singh S, Rutter JC, Therrien M, Yoon H, Lai ZW, Baublis A, Subramanian R, Devkota R, Small J, Sreekanth V, Han M, Lim D, Carpenter AE, Flannick J, Finucane H, Haigis MC, Claussnitzer M, Sheu E, Stevens B, Wagner BK, Choudhary A, Shaw JL, Pablo JL, Greka A.Cell Metab. 2023 May 2;35(5):887-905.e11. doi: 10.1016/j.cmet.2023.03.018. Epub 2023 Apr 18.PMID: 37075753

Molecular Determinants of Mitochondrial Shape and Function and Their Role in Glaucoma. Khalimonchuk O, Becker DF.Antioxid Redox Signal. 2023 May;38(13-15):896-919. doi: 10.1089/ars.2022.0124. Epub 2023 Jan 5.PMID: 36301938 Review.

Neonatal subgaleal hemorrhage: twenty years of trends in incidence, associations, and outcomes. Christensen TR, Bahr TM, Henry E, Ling CY, Hanton TH, Page JM, Ilstrup SJ, Carr NR, Ohls RK, Christensen RD.J Perinatol. 2023 May;43(5):573-577. doi: 10.1038/s41372-022-01541-z. Epub 2022 Oct 28.PMID: 36307481

Neonatal Intensive Care Unit Patients Receiving More Than 25 Platelet Transfusions. Bahr TM, Ohls RK, Ilstrup SJ, Christensen RD.Am J Perinatol. 2023 May 19. doi: 10.1055/a-2073-3848. Online ahead of print.PMID: 37054977

miRNA-1 promotes acute myeloid leukemia cell pathogenesis through metabolic regulation. Ghazaryan A, Wallace JA, Tang WW, Barba C, Lee SH, Bauer KM, Nelson MC, Kim CN, Stubben C, Voth WP, Rao DS, O’Connell RM.Front Genet. 2023 May 9;14:1192799. doi: 10.3389/fgene.2023.1192799. eCollection 2023.PMID: 37229187

Associations between blood donor sex and age, and outcomes of transfused newborn infants. Bahr TM, Christensen TR, Tweddell SM, Henry E, Rees T, Astin ME, Kelley WE, Ilstrup SJ, Ohls RK, Christensen RD.Transfusion. 2023 May 22. doi: 10.1111/trf.17417. Online ahead of print.PMID: 37218104

Temporal and spatial staging of lung alveolar regeneration is determined by the grainyhead transcription factor Tfcp2l1. Cardenas-Diaz FL, Liberti DC, Leach JP, Babu A, Barasch J, Shen T, Diaz-Miranda MA, Zhou S, Ying Y, Callaway DA, Morley MP, Morrisey EE.Cell Rep. 2023 May 30;42(5):112451. doi: 10.1016/j.celrep.2023.112451. Epub 2023 Apr 27.PMID: 37119134

Iron Homeostasis During Pregnancy: Maternal, Placental, and Fetal Regulatory Mechanisms. Sangkhae V, Fisher AL, Ganz TNemeth E.Annu Rev Nutr. 2023 May 30. doi: 10.1146/annurev-nutr-061021-030404. Online ahead of print.PMID: 37253681 Review.

Fetal Factors Disrupt Placental and Maternal Iron Homeostasis in Murine β-Thalassemia. Yu Y, Woloshun RR, Lee JK, Ebea PO, Zhu S, Nemeth E, Garrick L, Garrick M, Collins JF.Blood. 2023 May 5:blood.2022018839. doi: 10.1182/blood.2022018839. Online ahead of print.PMID: 37146247

 

2023 April

Vitamin E Induces Liver Iron Depletion and Alters Iron Regulation in Mice. Baratz E, Protchenko O, Jadhav S, Zhang D, Violet PC, Grounds S, Shakoury-Elizeh M, Levine M, Philpott CC.J Nutr. 2023 Apr 29:S0022-3166(23)37589-8. doi: 10.1016/j.tjnut.2023.04.018. Online ahead of print.PMID: 37127137

Oct1 cooperates with the Smad family of transcription factors to promote mesodermal lineage specification. Perovanovic J, Wu Y, Abewe H, Shen Z, Hughes EP, Gertz J, Chandrasekharan MB, Tantin D.Sci Signal. 2023 Apr 18;16(781):eadd5750. doi: 10.1126/scisignal.add5750. Epub 2023 Apr 18.PMID: 37071732

EnvIRONment modifies polycythemia vera. Prchal JT, Reeves BN.Blood. 2023 Apr 27;141(17):2042-2044. doi: 10.1182/blood.2023020065.PMID: 37103951

Metaboverse enables automated discovery and visualization of diverse metabolic regulatory patterns. Berg JA, Zhou Y, Ouyang Y, Cluntun AA, Waller TC, Conway ME, Nowinski SM, Van Ry T, George I, Cox JE, Wang B, Rutter J.Nat Cell Biol. 2023 Apr;25(4):616-625. doi: 10.1038/s41556-023-01117-9. Epub 2023 Apr 3.PMID: 37012464

Dersimelagon in Erythropoietic Protoporphyrias. Balwani M, Bonkovsky HL, Levy C, Anderson KE, Bissell DM, Parker C, Takahashi F, Desnick RJ, Belongie K; Endeavor Investigators.N Engl J Med. 2023 Apr 13;388(15):1376-1385. doi: 10.1056/NEJMoa2208754.PMID: 37043653

B-1 plasma cells require non-cognate CD4 T cell help to generate a unique repertoire of natural IgM. Smith FL, Savage HP, Luo Z, Tipton CM, Lee FE, Apostol AC, Beaudin AE, Lopez DA, Jensen I, Keller S, Baumgarth N. J Exp Med. 2023 Apr 3;220(4):e20220195. doi: 10.1084/jem.20220195. Epub 2023 Feb 22.PMID: 36811605

Pathogenic Mechanisms in Thalassemia II: Iron Overload. Ganz T, Nemeth E. Hematol Oncol Clin North Am. 2023 Apr;37(2):353-363. doi: 10.1016/j.hoc.2022.12.006.PMID: 36907608

 

2023 March

How I diagnose and treat acute graft-versus-host disease after solid organ transplantation. Cooper JP, Abkowitz JL.Blood. 2023 Mar 9;141(10):1136-1146. doi: 10.1182/blood.2022015954.PMID: 36395067

A Rationally Designed Complex Replenishes the Transferrin Iron Pool Directly and with High Specificity. Sargun A, Fisher AL, Wolock AS, Phillips S, Sojoodi M, Khanna S, Babitt JL, Gale EM.J Am Chem Soc. 2023 Mar 29;145(12):6871-6879. doi: 10.1021/jacs.3c00123. Epub 2023 Mar 15.PMID: 36920018

Tissue factor activity of small and large extracellular vesicles in different diseases. Sachetto ATA, Archibald SJ, Hisada Y, Rosell A, Havervall S, van Es N, Nieuwland R, Campbell RA, Middleton EA, Rondina MT, Thålin C, Mackman N.Res Pract Thromb Haemost. 2023 Mar;7(3):100124. doi: 10.1016/j.rpth.2023.100124. Epub 2023 Mar 15.PMID: 37012986

Bacteroides thetaiotaomicron, a Model Gastrointestinal Tract Species, Prefers Heme as an Iron Source, Yields Protoporphyrin IX as a Product, and Acts as a Heme Reservoir. Meslé MM, Gray CR, Dlakić M, DuBois JL.Microbiol Spectr. 2023 Mar 2;11(2):e0481522. doi: 10.1128/spectrum.04815-22. Online ahead of print.PMID: 36862015

Isolation and Characterization of Fetal Liver Hematopoietic Stem Cells. López DA, Beaudin AE. Methods Mol Biol. 2023;2567:99-112. doi: 10.1007/978-1-0716-2679-5_7.PMID: 36255697

A Rationally Designed Complex Replenishes the Transferrin Iron Pool Directly and with High Specificity. Sargun A, Fisher AL, Wolock AS, Phillips S, Sojoodi M, Khanna S, Babitt JL, Gale EM. J Am Chem Soc. 2023 Mar 15. doi: 10.1021/jacs.3c00123. Online ahead of print.PMID: 36920018

Downregulated KLF2 in polycythemia vera and essential thrombocythemia induces prothrombotic gene expression. Song J, Kim SJ, Gollamudi J, Thiagarajan P, Prchal JT. Blood Adv. 2023 Mar 14;7(5):712-717. doi: 10.1182/bloodadvances.2022008052.PMID: 36343116

Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase. Hicks KG, Cluntun, AA, Schubert HL, Hackett, SR, Berg, JA, Leonard PG, Cox JE, Rutter J +36 authors , Science 9 Mar 2023 Vol 379, Issue 6636 pp. 996-1003.

Recessive pathogenic variants in MCAT cause combined oxidative phosphorylation deficiency. Webb BD, Nowinski SM, Solmonson A, Ganesh J, Rodenburg RJ, Leandro J, Evans A, Vu HS, Naidich TP, Gelb BD, DeBerardinis RJ, Rutter J, Houten SM. Elife. 2023 Mar 7;12:e68047. doi: 10.7554/eLife.68047.PMID: 36881526

Transferred mitochondria accumulate reactive oxygen species, promoting proliferation. Kidwell CU, Casalini JR, Pradeep S, Scherer SD, Greiner D, Bayik D, Watson DC, Olson GS, Lathia JD, Johnson JS, Rutter J, Welm AL, Zangle TA, Roh-Johnson M. Elife. 2023 Mar 6;12:e85494. doi: 10.7554/eLife.85494. Online ahead of print.PMID: 36876914

On the cutting edge: perspectives in bioenergetics. Granath-Panelo M, Krook A, Rutter J, Kajimura S. Nat Rev Endocrinol. 2023 Mar 3. doi: 10.1038/s41574-023-00820-9. Online ahead of print.PMID: 36869239

 

2023 February

Iron and the Pathophysiology of Diabetes. Harrison AV, Lorenzo FR, McClain DA.Annu Rev Physiol. 2023 Feb 10;85:339-362. doi: 10.1146/annurev-physiol-022522-102832. Epub 2022 Sep 22.PMID: 36137277

Structures of LRP2 reveal a molecular machine for endocytosis. Beenken A, Cerutti G, Brasch J, Guo Y, Sheng Z, Erdjument-Bromage H, Aziz Z, Robbins-Juarez SY, Chavez EY, Ahlsen G, Katsamba PS, Neubert TA, Fitzpatrick AWP, Barasch J, Shapiro L.Cell. 2023 Feb 16;186(4):821-836.e13. doi: 10.1016/j.cell.2023.01.016. Epub 2023 Feb 6.PMID: 36750096

Redox Regulation and Metabolic Dependency of Zika Virus Replication: Inhibition by Nrf2-Antioxidant Response and NAD(H) Antimetabolites. Sahoo BR, Crook AA, Pattnaik A, Torres-Gerena AD, Khalimonchuk O, Powers R, Franco R, Pattnaik AK. J Virol. 2023 Feb 28;97(2):e0136322. doi: 10.1128/jvi.01363-22. Epub 2023 Jan 23.PMID: 36688653

Structural homology screens reveal poxvirus-encoded proteins impacting inflammasome-mediated defenses. Boys IN, Johnson AG, Quinlan M, Kranzusch PJ, Elde NC. bioRxiv. 2023 Feb 27:2023.02.26.529821. doi: 10.1101/2023.02.26.529821. Preprint.PMID: 36909515

A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution. Chen YH, Tian W, Yasuda M, Ye Z, Song M, Mandel U, Kristensen C, Povolo L, Marques ARA, Čaval T, Heck AJR, Sampaio JL, Johannes L, Tsukimura T, Desnick R, Vakhrushev SY, Yang Z, Clausen H. Front Bioeng Biotechnol. 2023 Feb 24;11:1128371. doi: 10.3389/fbioe.2023.1128371. eCollection 2023.PMID: 36911201

Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis. Johnson JM, Peterlin AD, Balderas E, Sustarsic EG, Maschek JA, Lang MJ, Jara-Ramos A, Panic V, Morgan JT, Villanueva CJ, Sanchez A, Rutter J, Lodhi IJ, Cox JE, Fisher-Wellman KH, Chaudhuri D, Gerhart-Hines Z, Funai K. Sci Adv. 2023 Feb 24;9(8):eade7864. doi: 10.1126/sciadv.ade7864. Epub 2023 Feb 24.PMID: 36827367

Elevated Transferrin at High Altitude: Trick or Treat? Vinchi F.Hemasphere. 2023 Feb 23;7(3):e850. doi: 10.1097/HS9.0000000000000850. eCollection 2023 Mar.PMID: 36844187

Impact of Cryopreservation on Extracorporeal Photopheresis (ECP)-Treated Leukocyte Subsets. Trunk AD, Radwanski K, Heber C, Taylor A, Hsieh F, Harris A, Lee CJ, Phillips JD, Couriel DR. Transplant Cell Ther. 2023 Feb 23:S2666-6367(23)01127-2. doi: 10.1016/j.jtct.2023.02.017. Online ahead of print.PMID: 36828177

Interferon Gamma-Inducible NAMPT in Melanoma Cells Serves as a Mechanism of Resistance to Enhance Tumor Growth. Barba C, Ekiz HA, Tang WW, Ghazaryan A, Hansen M, Lee SH, Voth WP, O’Connell RM.C ancers (Basel). 2023 Feb 23;15(5):1411. doi: 10.3390/cancers15051411.PMID: 36900204

Lack of evidence that fibrillin1 regulates bone morphogenetic protein 4 activity in kidney or lung. McKnite A, Kim HS, Silva J, Christian JL. Dev Dyn. 2023 Feb 23. doi: 10.1002/dvdy.578. Online ahead of print.PMID: 36825302

Oct4 redox sensitivity potentiates iPSC reprogramming. Shen Z, Wu Y, Manna A, Chandrasekhara MB, Tantin D.bioRxiv. 2023 Feb 21:2023.02.21.529404. doi: 10.1101/2023.02.21.529404. Preprint.PMID: 36865286

FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity. Wieder N, Fried JC, Kim C, Sidhom EH, Brown MR, Marshall JL, Arevalo C, Dvela-Levitt M, Kost-Alimova M, Sieber J, Gabriel KR, Pacheco J, Clish C, Abbasi HS, Singh S, Rutter J, Therrien M, Yoon H, Lai ZW, Baublis A, Subramanian R, Devkota R, Small J, Sreekanth V, Han M, Lim D, Carpenter AE, Flannick J, Finucane H, Haigis MC, Claussnitzer M, Sheu E, Stevens B, Wagner BK, Choudhary A, Shaw JL, Pablo JL, Greka A. bioRxiv. 2023 Feb 20:2023.02.19.529127. doi: 10.1101/2023.02.19.529127. Preprint.PMID: 36865221


Proteomic Analysis of Ferrochelatase Interactome in Erythroid and Non-Erythroid Cells.
Obi CD, Dailey HA, Jami-Alahmadi Y, Wohlschlegel JA, Medlock AE. Life (Basel). 2023 Feb 18;13(2):577. doi: 10.3390/life13020577.PMID: 36836934

Consensus Statement on the definition and classification of metabolic hyperferritinaemia. Valenti L, Corradini E, Adams LA, Aigner E, Alqahtani S, Arrese M, Bardou-Jacquet E, Bugianesi E, Fernandez-Real JM, Girelli D, Hagström H, Henninger B, Kowdley K, Ligabue G, McClain D, Lainé F, Miyanishi K, Muckenthaler MU, Pagani A, Pedrotti P, Pietrangelo A, Prati D, Ryan JD, Silvestri L, Spearman CW, Stål P, Tsochatzis EA, Vinchi F, Zheng MH, Zoller H. Nat Rev Endocrinol. 2023 Feb 17:1-12. doi: 10.1038/s41574-023-00807-6. Online ahead of print.PMID: 36805052

MicroRNA-155 Plays Selective Cell-Intrinsic Roles in Brain-Infiltrating Immune Cell Populations during Neuroinflammation. Thompson JW, Hu R, Huffaker TB, Ramstead AG, Ekiz HA, Bauer KM, Tang WW, Ghazaryan A, Round JL, Fujinami RS, O’Connell RM. J Immunol. 2023 Feb 17:ji2200478. doi: 10.4049/jimmunol.2200478. Online ahead of print.PMID: 36883849

Structures of LRP2 reveal a molecular machine for endocytosis. Beenken A, Cerutti G, Brasch J, Guo Y, Sheng Z, Erdjument-Bromage H, Aziz Z, Robbins-Juarez SY, Chavez EY, Ahlsen G, Katsamba PS, Neubert TA, Fitzpatrick AWP, Barasch J, Shapiro L. Cell. 2023 Feb 16;186(4):821-836.e13. doi: 10.1016/j.cell.2023.01.016. Epub 2023 Feb 6.PMID: 36750096

Iron and the Pathophysiology of Diabetes. Harrison AV, Lorenzo FR, McClain DA. Annu Rev Physiol. 2023 Feb 10;85:339-362. doi: 10.1146/annurev-physiol-022522-102832. Epub 2022 Sep 22.PMID: 36137277


Iron is a modifier of the phenotypes of JAK2-mutant myeloproliferative neoplasms.
Stetka J, Usart M, Kubovcakova L, Rai S, Nageswara Rao T, Sutter J, Hao-Shen H, Dirnhofer S, Geier F, Bader MS, Passweg JR, Manolova V, Dürrenberger F, Ahmed N, Schroeder T, Ganz T, Nemeth E, Silvestri L, Nai A, Camaschella C, Skoda RC. Blood. 2023 Feb 9:blood.2022017976. doi: 10.1182/blood.2022017976. Online ahead of print.PMID: 36758212

Role of the Mycobacterium tuberculosis ESX-4 Secretion System in Heme Iron Utilization and Pore Formation by PPE Proteins. Sankey N, Merrick H, Singh P, Rogers J, Reddi A, Hartson SD, Mitra A.mSphere. 2023 Feb 7:e0057322. doi: 10.1128/msphere.00573-22. Online ahead of print.PMID: 36749044

Systematically testing human HMBS missense variants to reveal mechanism and pathogenic variation. van Loggerenberg W, Sowlati-Hashjin S, Weile J, Hamilton R, Chawla A, Gebbia M, Kishore N, Frésard L, Mustajoki S, Pischik E, Pierro ED, Barbaro M, Floderus Y, Schmitt C, Gouya L, Colavin A, Nussbaum R, Friesema ECH, Kauppinen R, To-Figueras J, Aarsand AK, Desnick RJ, Garton M, Roth FP. bioRxiv. 2023 Feb 6:2023.02.06.527353. doi: 10.1101/2023.02.06.527353. Preprint.PMID: 36798224

Iron-tracking strategies: Chaperones capture iron in the cytosolic labile iron pool. Philpott CC, Protchenko O, Wang Y, Novoa-Aponte L, Leon-Torres A, Grounds S, Tietgens AJ. Front Mol Biosci. 2023 Feb 2;10:1127690. doi: 10.3389/fmolb.2023.1127690. eCollection 2023.PMID: 36818045

 

2023 January

Neonatal NET-Inhibitory Factor improves survival in the cecal ligation and puncture model of polymicrobial sepsis by inhibiting neutrophil extracellular traps. de Araujo CV, Denorme F, Stephens WZ, Li Q, Cody MJ, Crandell JL, Petrey AC, Queisser KA, Rustad JL, Fulcher JM, Evangelista JL, Kay MS, Schiffman JD, Campbell RA, Yost CC.Front Immunol. 2023 Jan 17;13:1046574. doi: 10.3389/fimmu.2022.1046574. eCollection 2022.PMID: 36733389

Nef enhances HIV-1 replication and infectivity independently of SERINC5 in CEM T cells. Ramirez PW, Vollbrecht T, Acosta FM, Suarez M, Angerstein AO, Wallace J, O’ Connell RM, Guatelli J. Virology. 2023 Jan;578:154-162. doi: 10.1016/j.virol.2022.12.008. Epub 2022 Dec 23.PMID: 36577173

Nucleated Red Blood Cell Emergence-Time in Newborn Lambs Following a Dose of Darbepoetin Alfa. Bahr TM, Albertine KH, Christensen RD, Dahl MJ, Rebentisch A, Dawson E, Major E, Foreman H, Headden D, Vordos Z, Nabi A, Pettet L, Badrov P, Addison C, Christensen DR. Curr Pediatr Rev. 2023;19(4):425-428. doi: 10.2174/1573396319666221219153902.PMID: 36537595

Perinatal Hemolytic Disorders and Identification Using End Tidal Breath Carbon Monoxide. Christensen RD, Bahr TM, Pakdeeto S, Supapannachart S, Zhang H. Curr Pediatr Rev. 2023;19(4):376-387. doi: 10.2174/1573396319666221220095522.PMID: 36545740 Review.

Intramuscular administration of glyoxylate rescues swine from lethal cyanide poisoning and ameliorates the biochemical sequalae of cyanide intoxication. Bebarta VS, Shi X, Zheng S, Hendry-Hofer TB, Severance CC, Behymer MM, Boss GR, Mahon S, Brenner M, Knipp GT, Davisson VJ, Peterson RT, MacRae CA, Rutter J, Gerszten RE, Nath AK. Toxicol Sci. 2023 Jan 31;191(1):90-105. doi: 10.1093/toxsci/kfac116.PMID: 36326479

Direct Tests of Cytochrome Function in the Electron Transport Chain of Malaria Parasites. Espino-Sanchez TJ, Wienkers H, Marvin RG, Nalder SA, Garc A-Guerrero AE, VanNatta PE, Jami-Alahmadi Y, Blackwell AM, Whitby FG, Wohlschlegel JA, Kieber-Emmons MT, Hill CP, Sigala PA.bioRxiv. 2023 Jan 23:2023.01.23.525242. doi: 10.1101/2023.01.23.525242. Preprint.PMID: 36747727

TMPRSS6 as a Therapeutic Target for Disorders of Erythropoiesis and Iron Homeostasis. Ganz T, Nemeth E, Rivella S, Goldberg P, Dibble AR, McCaleb ML, Guo S, Monia BP, Barrett TD. Adv Ther. 2023 Jan 23. doi: 10.1007/s12325-022-02421-w. Online ahead of print.PMID: 36690839

Depletion Assisted Hemin Affinity (DAsHA) Proteomics Reveals an Expanded Landscape of Heme Binding Proteins in the Human Proteome. Kim H, Moore CM, Mestre-Fos S, Hanna DA, Williams LD, Reddi AR, Torres MP.Metallomics. 2023 Jan 20:mfad004. doi: 10.1093/mtomcs/mfad004. Online ahead of print.PMID: 36669767

Placental abruption and neonatal anemia. Tweddell SM, Bahr TM, Henry E, Page JM, Ilstrup SJ, Ohls RK, Christensen RD. J Perinatol. 2023 Jan 17. doi: 10.1038/s41372-023-01603-w. Online ahead of print.PMID: 36650233

Iron-dependent post transcriptional control of mitochondrial aconitase expression. Shen M, Goforth JB, Eisenstein RS. Metallomics. 2023 Jan 10;15(1):mfac099. doi: 10.1093/mtomcs/mfac099.PMID: 36702557

Molecular Determinants of Mitochondrial Shape and Function and Their Role in Glaucoma. Khalimonchuk O, Becker DF. Antioxid Redox Signal. 2023 Jan 5. doi: 10.1089/ars.2022.0124. Online ahead of print.PMID: 36301938