Publications

Recent Publications

2022 July

Implications of an Elevated Nucleated Red Blood Cell Count in Neonates with Moderate to Severe Hypoxic-Ischemic Encephalopathy. Bahr TM, Ohls RK, Baserga MC, Lawrence SM, Winter SL, Christensen RD.J Pediatr. 2022 Jul;246:12-18.e2. doi: 10.1016/j.jpeds.2022.04.015. Epub 2022 Apr 14.PMID: 35430249

International guidelines regarding the role of IVIG in the management of Rh- and ABO-mediated haemolytic disease of the newborn. Lieberman L, Lopriore E, Baker JM, Bercovitz RS, Christensen RD, Crighton G, Delaney M, Goel R, Hendrickson JE, Keir A, Landry D, La Rocca U, Lemyre B, Maier RF, Muniz-Diaz E, Nahirniak S, New HV, Pavenski K, Dos Santos MCP, Ramsey G, Shehata N; International Collaboration for Transfusion Medicine Guidelines (ICTMG).Br J Haematol. 2022 Jul;198(1):183-195. doi: 10.1111/bjh.18170. Epub 2022 Apr 12.PMID: 35415922

Metal content and kinetic properties of yeast RNA lariat debranching enzyme Dbr1. Clark NE, Katolik A, Taggart AJ, Buerer L, Holloway SP, Miller N, Phillips JD, Farrell CP, Damha MJ, Fairbrother WG.RNA. 2022 Jul;28(7):927-936. doi: 10.1261/rna.079159.122. Epub 2022 Apr 22.PMID: 35459748

 

2022 June

ATG4A regulates human erythroid maturation and mitochondrial clearance. Stolla MC, Reilly A, Bergantinos R, Stewart S, Thom N, Clough CA, Wellington RC, Stolitenko R, Abkowitz JL, Doulatov S.Blood Adv. 2022 Jun 28;6(12):3579-3589. doi: 10.1182/bloodadvances.2021005910.PMID: 35443024

Cancer cells depend on environmental lipids for proliferation when electron acceptors are limited. Li Z, Ji BW, Dixit PD, Tchourine K, Lien EC, Hosios AM, Abbott KL, Rutter JC, Westermark AM, Gorodetsky EF, Sullivan LB, Vander Heiden MG, Vitkup D.Nat Metab. 2022 Jun;4(6):711-723. doi: 10.1038/s42255-022-00588-8. Epub 2022 Jun 23.PMID: 35739397

Erythropoietic effects of vadadustat in patients with anemia associated with chronic kidney disease. Koury MJ, Agarwal R, Chertow GM, Eckardt KU, Fishbane S, Ganz T, Haase VH, Hanudel MR, Parfrey PS, Pergola PE, Roy-Chaudhury P, Tumlin JA, Anders R, Farag YMK, Luo W, Minga T, Solinsky C, Vargo DL, Winkelmayer WC.Am J Hematol. 2022 Jun 25. doi: 10.1002/ajh.26644. Online ahead of print.PMID: 35751858

Coordination of metal center biogenesis in human cytochrome c oxidase. Nývltová E, Dietz JV, Seravalli J, Khalimonchuk O, Barrientos A.Nat Commun. 2022 Jun 24;13(1):3615. doi: 10.1038/s41467-022-31413-1.PMID: 35750769

Ferric pyrophosphate citrate for parenteral administration of maintenance iron: structure, mechanism of action, clinical efficacy and safety. Fishbane S, Ganz T, Pratt RD.Curr Med Res Opin. 2022 Jun 21:1-36. doi: 10.1080/03007995.2022.2092373. Online ahead of print.PMID: 35726771

Tet2 coordinates with Foxo1 and Runx1 to balance T follicular helper cell and T helper 1 cell differentiation. Baessler A, Novis CL, Shen Z, Perovanovic J, Wadsworth M, Thiede KA, Sircy LM, Harrison-Chau M, Nguyen NX, Varley KE, Tantin D, Hale JS.Sci Adv. 2022 Jun 17;8(24):eabm4982. doi: 10.1126/sciadv.abm4982. Epub 2022 Jun 15.PMID: 35704571

Phase 1/2 Trial of CLAG-M with Dose-Escalated Mitoxantrone in Combination with Fractionated-Dose Gemtuzumab Ozogamicin for Newly Diagnosed Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms. Godwin CD, Rodríguez-Arbolí E, Othus M, Halpern AB, Appelbaum JS, Percival MM, Hendrie PC, Oehler VG, Keel SB, Abkowitz JL, Cooper JP, Cassaday RD, Estey EH, Walter RB.Cancers (Basel). 2022 Jun 14;14(12):2934. doi: 10.3390/cancers14122934.PMID: 35740603

Protocol for engineering and validating a synthetic mitochondrial intermembrane bridge in mammalian cells. Purohit G, Viana MP, Khalimonchuk O.STAR Protoc. 2022 Jun 14;3(3):101454. doi: 10.1016/j.xpro.2022.101454. eCollection 2022 Sep 16.PMID: 35719722

Studies of a mosaic patient with DBA and chimeric mice reveal erythroid cell-extrinsic contributions to erythropoiesis. Doty RT, Fan X, Young DJ, Liang J, Singh K, Pakbaz Z, Desmond R, Young-Baird SK, Chandrasekharappa SC, Donovan FX, Phelps SR, Winkler T, Dunbar CE, Abkowitz JL.Blood. 2022 Jun 9;139(23):3439-3449. doi: 10.1182/blood.2021013507.PMID: 35349664

P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia. Lin KH, Rutter JC, Xie A, Killarney ST, Vaganay C, Benaksas C, Ling F, Sodaro G, Meslin PA, Bassil CF, Fenouille N, Hoj J, Washart R, Ang HX, Cerda-Smith C, Chaintreuil P, Jacquel A, Auberger P, Forget A, Itzykson R, Lu M, Lin J, Pierobon M, Sheng Z, Li X, Chilkoti A, Owzar K, Rizzieri DA, Pardee TS, Benajiba L, Petricoin E, Puissant A, Wood KC.Nat Cancer. 2022 Jun 6. doi: 10.1038/s43018-022-00394-x. Online ahead of print.PMID: 35668193

Severe anemia at birth – incidence and implications. Bahr TM, Lawrence SM, Henry E, Ohls RK, Li S, Christensen RD.J Pediatr. 2022 Jun 1:S0022-3476(22)00516-9. doi: 10.1016/j.jpeds.2022.05.045. Online ahead of print.PMID: 35660494

 

2022 May

Hepcidin is elevated in primary and secondary myelofibrosis and remains elevated in patients treated with ruxolitinib.  Zhou A, Kong T, Fowles JS, Jung CL, Allen MJ, Fisher DAC, Fulbright M, Nemeth E, Ganz T, Oh ST. Br J Haematol. 2022 May;197(4):e49-e52. doi: 10.1111/bjh.18044. Epub 2022 Feb 6. PMID: 35128632

Antibody-Mediated Targeting of a Hybrid-Insulin-Peptide Towards Neonatal Thymic Langerin+ Cells Enhances T Cell Central Tolerance and Delays Autoimmune Diabetes. Lin Y, Perovanovic J, Kong Y, Igyarto BZ, Zurawski S, Tantin D, Zurawski G, Bettini M, Bettini ML.Diabetes. 2022 May 27:db211069. doi: 10.2337/db21-1069. Online ahead of print.PMID: 35622068

Prime Real Estate: Metals, Cofactors and MICOS. Medlock AE, Hixon JC, Bhuiyan T, Cobine PA.Front Cell Dev Biol. 2022 May 20;10:892325. doi: 10.3389/fcell.2022.892325. eCollection 2022.PMID: 35669513 Free PMC article. Review.

Ferrochelatase: Mapping the Intersection of Iron and Porphyrin Metabolism in the Mitochondria. Obi CD, Bhuiyan T, Dailey HAMedlock AE.Front Cell Dev Biol. 2022 May 12;10:894591. doi: 10.3389/fcell.2022.894591. eCollection 2022.PMID: 35646904

Quantitating Iron Transport across the Mouse Placenta In Vivo using Nonradioactive Iron Isotopes. Sangkhae V, Nemeth E.J Vis Exp. 2022 May 10;(183). doi: 10.3791/63378.PMID: 35635455

Molecular Mechanisms of Iron and Heme Metabolism.  Dutt S, Hamza I, Bartnikas TB. Annu Rev Nutr. 2022 May 4. doi: 10.1146/annurev-nutr-062320-112625. Online ahead of print. PMID: 35508203

 

2022 April

Enteral ferric citrate absorption is dependent on the iron transport protein ferroportin.  Hanudel MR, Czaya B, Wong S, Rappaport M, Namjoshi S, Chua K, Jung G, Gabayan V, Qiao B, Nemeth E, Ganz T. Kidney Int. 2022 Apr;101(4):711-719. doi: 10.1016/j.kint.2021.10.036. Epub 2021 Nov 25. PMID: 34838540

Posttranslational regulation of mitochondrial frataxin and identification of compounds that increase frataxin levels in Friedreich’s ataxia.  Hackett PT, Jia X, Li L, Ward DM. J Biol Chem. 2022 Apr 25;298(6):101982. doi: 10.1016/j.jbc.2022.101982. Online ahead of print. PMID: 35472330

Renoprotective effects of ferric citrate in a mouse model of chronic kidney disease.  Hanudel MR, Czaya B, Wong S, Jung G, Chua K, Qiao B, Gabayan V, Ganz T. Sci Rep. 2022 Apr 23;12(1):6695. doi: 10.1038/s41598-022-10842-4. PMID: 35461329 Free PMC article.

Metal content and kinetic properties of yeast RNA lariat debranching enzyme Dbr1.  Clark N, Katolik A, Taggart AJ, Buerer L, Holloway S, Miller N, Phillips JD, Farrell CP, Damha MJ, Fairbrother W. RNA. 2022 Apr 22:rna.079159.122. doi: 10.1261/rna.079159.122. Online ahead of print. PMID: 35459748

ATG4A regulates human erythroid maturation and mitochondrial clearance.  Stolla MC, Reilly A, Bergantinos R, Stewart S, Thom N, Clough CA, Wellington RC, Stolitenko R, Abkowitz JL, Doulatov S. Blood Adv. 2022 Apr 20:bloodadvances.2021005910. doi: 10.1182/bloodadvances.2021005910. Online ahead of print. PMID: 35443024

IL7Rα, but not Flk2, is required for hematopoietic stem cell reconstitution of tissue-resident lymphoid cells.  Worthington AK, Cool T, Poscablo DM, Hussaini A, Beaudin AE, Forsberg EC. Development. 2022 Apr 15;149(8):dev200139. doi: 10.1242/dev.200139. Epub 2022 Jan 24. PMID: 35072209

Implications of an Elevated Nucleated Red Blood Cell Count in Neonates with Moderate to Severe Hypoxic-Ischemic Encephalopathy.  Bahr TM, Ohls RK, Baserga MC, Lawrence SM, Winter SL, Christensen RD. J Pediatr. 2022 Apr 14:S0022-3476(22)00329-8. doi: 10.1016/j.jpeds.2022.04.015. Online ahead of print. PMID: 35430249

International guidelines regarding the role of IVIG in the management of Rh- and ABO-mediated haemolytic disease of the newborn.  Lieberman L, Lopriore E, Baker JM, Bercovitz RS, Christensen RD, Crighton G, Delaney M, Goel R, Hendrickson JE, Keir A, Landry D, La Rocca U, Lemyre B, Maier RF, Muniz-Diaz E, Nahirniak S, New HV, Pavenski K, Dos Santos MCP, Ramsey G, Shehata N; International Collaboration for Transfusion Medicine Guidelines (ICTMG). Br J Haematol. 2022 Apr 12. doi: 10.1111/bjh.18170. Online ahead of print. PMID: 35415922

Recurrent evolution of an inhibitor of ESCRT-dependent virus budding and LINE-1 retrotransposition in primates.  Rheinemann L, Downhour DM, Davenport KA, McKeown AN, Sundquist WI, Elde NC. Curr Biol. 2022 Apr 11;32(7):1511-1522.e6. doi: 10.1016/j.cub.2022.02.018. Epub 2022 Mar 3. PMID: 35245459

Lamin B1 deletion in myeloid neoplasms causes nuclear anomaly and altered hematopoietic stem cell function.  Reilly A, Philip Creamer J, Stewart S, Stolla MC, Wang Y, Du J, Wellington R, Busch S, Estey EH, Becker PS, Fang M, Keel SB, Abkowitz JL, Soma LA, Ma J, Duan Z, Doulatov S. Cell Stem Cell. 2022 Apr 7;29(4):577-592.e8. doi: 10.1016/j.stem.2022.02.010. Epub 2022 Mar 11. PMID: 35278369

Perspective: Pivotal translational hematology and therapeutic insights in chronic myeloid hematopoietic stem cell malignancies.  Mughal TI, Pemmaraju N, Bejar R, Gale RP, Bose P, Kiladjian JJ, Prchal J, Royston D, Pollyea D, Valent P, Brümmendorf TH, Skorski T, Patnaik M, Santini V, Fenaux P, Kucine N, Verstovsek S, Mesa R, Barbui T, Saglio G, Van Etten RA. Hematol Oncol. 2022 Apr 3. doi: 10.1002/hon.2987. Online ahead of print. PMID: 35368098

GFI1 Cooperates with IKZF1/IKAROS to Activate Gene Expression in T-cell Acute Lymphoblastic Leukemia.  Sun W, Guo J, McClellan D, Poeschla A, Bareyan D, Casey MJ, Cairns BR, Tantin D, Engel ME. Mol Cancer Res. 2022 Apr 1;20(4):501-514. doi: 10.1158/1541-7786.MCR-21-0352. PMID: 34980595

 

2022 March

Coordinated missplicing of TMEM14C and ABCB7 causes ring sideroblast formation in SF3B1-mutant myelodysplastic syndrome.  Clough CA, Pangallo J, Sarchi M, Ilagan JO, North K, Bergantinos R, Stolla MC, Naru J, Nugent P, Kim E, Stirewalt DL, Subramaniam AR, Abdel-Wahab O, Abkowitz JL, Bradley RK, Doulatov S. Blood. 2022 Mar 31;139(13):2038-2049. doi: 10.1182/blood.2021012652. PMID: 34861039

An Infant With Hereditary Fructose Intolerance and a Novel Presentation of Disseminated Intravascular Coagulopathy following Pyloromyotomy.  Aldag E, Fan EM, Marshall I, Christensen RD, Shayota BJ, Meznarich JA. J Pediatr Hematol Oncol. 2022 Mar 30. doi: 10.1097/MPH.0000000000002443. Online ahead of print. PMID: 35398868

Studies in a mosaic DBA patient and chimeric mice reveal erythroid cell-extrinsic contributions to erythropoiesis.  Doty RT, Fan X, Young DJ, Liang JA, Singh K, Pakbaz Z, Desmond R, Young-Baird SK, Chandrasekharappa SC, Donovan FX, Phelps S, Winkler T, Dunbar CE, Abkowitz JL. Blood. 2022 Mar 29:blood.2021013507. doi: 10.1182/blood.2021013507. Online ahead of print. PMID: 35349664

Glyoxylate protects against cyanide toxicity through metabolic modulation.  Nielson JR, Nath AK, Doane KP, Shi X, Lee J, Tippetts EG, Saha K, Morningstar J, Hicks KG, Chan A, Zhao Y, Kelly A, Hendry-Hofer TB, Witeof A, Sips PY, Mahon S, Bebarta VS, Davisson VJ, Boss GR, Rutter J, MacRae CA, Brenner M, Gerszten RE, Peterson RT. Sci Rep. 2022 Mar 23;12(1):4982. doi: 10.1038/s41598-022-08803-y. PMID: 35322094

Snapshots of nascent RNA reveal cell- and stimulus-specific responses to acute kidney injury.  Shen TH, Stauber J, Xu K, Jacunski A, Paragas N, Callahan M, Banlengchit R, Levitman AD, Desanti De Oliveira B, Beenken A, Grau MS, Mathieu E, Zhang Q, Li Y, Gopal T, Askanase N, Arumugam S, Mohan S, Good PI, Stevens JS, Lin F, Sia SK, Lin CS, D’Agati V, Kiryluk K, Tatonetti NP, Barasch J. JCI Insight. 2022 Mar 22;7(6):e146374. doi: 10.1172/jci.insight.146374. PMID: 35230973

Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling.  Czaya B, Heitman K, Campos I, Yanucil C, Kentrup D, Westbrook D, Gutierrez O, Babitt JL, Jung G, Salusky IB, Hanudel M, Faul C. Elife. 2022 Mar 18;11:e74782. doi: 10.7554/eLife.74782. PMID: 35302487

SPOTting stress at the mitochondrial outer membrane.  Schuler MH, Hughes AL. Mol Cell. 2022 Mar 17;82(6):1086-1088. doi: 10.1016/j.molcel.2022.02.030. PMID: 35303482

Critical role for isoprenoids in apicoplast biogenesis by malaria parasites.  Okada M, Rajaram K, Swift RP, Mixon A, Maschek JA, Prigge ST, Sigala PA. Elife. 2022 Mar 8;11:e73208. doi: 10.7554/eLife.73208. PMID: 35257658

Human defensin-inspired discovery of peptidomimetic antibiotics.  Luo G, Zhang J, Wang H, Sun Y, Cheng B, Xu Z, Zhang Y, Li H, Lu W, Nemeth E, Ganz T, Fang X. Proc Natl Acad Sci U S A. 2022 Mar 8;119(10):e2117283119. doi: 10.1073/pnas.2117283119. Epub 2022 Mar 1. PMID: 35238683

Acellular human amniotic fluid protects the ischemic-reperfused rat myocardium.  Lee YS, Javan H, Reems JA, Li L, Lusty J, Schaaf CI, Pierce J, Phillips JD, Selzman CH. Am J Physiol Heart Circ Physiol. 2022 Mar 1;322(3):H406-H416. doi: 10.1152/ajpheart.00331.2021. Epub 2022 Jan 21. PMID: 35060752

 

2022 February

Heme oxygenase-2 (HO-2) binds and buffers labile ferric heme in human embryonic kidney cells.  Hanna DA, Moore CM, Liu L, Yuan X, Dominic IM, Fleischhacker AS, Hamza I, Ragsdale SW, Reddi AR. J Biol Chem. 2022 Feb;298(2):101549. doi: 10.1016/j.jbc.2021.101549. Epub 2021 Dec 29. PMID: 34973332

Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency.  De La Rossa A, Laporte MH, Astori S, Marissal T, Montessuit S, Sheshadri P, Ramos-Fernández E, Mendez P, Khani A, Quairiaux C, Taylor EB, Rutter J, Nunes JM, Carleton A, Duchen MR, Sandi C, Martinou JC. Elife. 2022 Feb 21;11:e72595. doi: 10.7554/eLife.72595. PMID: 35188099

ABCB6 polymorphisms are not overly represented in patients with porphyria.  Farrell CP, Nicolas G, Desnick RJ, Parker CJ, Lamoril J, Gouya L, Karim Z, Tchernitchko D, Chan B, Puy H, Phillips JD. Blood Adv. 2022 Feb 8;6(3):760-766. doi: 10.1182/bloodadvances.2021005484. PMID: 34724702

MRP5 and MRP9 play a concerted role in male reproduction and mitochondrial function.  Chambers IG, Kumar P, Lichtenberg J, Wang P, Yu J, Phillips JD, Kane MA, Bodine D, Hamza I. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2111617119. doi: 10.1073/pnas.2111617119. PMID: 35121660

Natural rodent model of viral transmission reveals biological features of virus population dynamics. Fay EJ, Balla KM, Roach SN, Shepherd FK, Putri DS, Wiggen TD, Goldstein SA, Pierson MJ, Ferris MT, Thefaine CE, Tucker A, Salnikov M, Cortez V, Compton SR, Kotenko SV, Hunter RC, Masopust D, Elde NC, Langlois RA. J Exp Med. 2022 Feb 7;219(2):e20211220. doi: 10.1084/jem.20211220. Epub 2021 Dec 27. PMID: 34958350

Hepcidin is elevated in primary and secondary myelofibrosis and remains elevated in patients treated with ruxolitinib.  Zhou A, Kong T, Fowles JS, Jung CL, Allen MJ, Fisher DAC, Fulbright M, Nemeth E, Ganz T, Oh ST. Br J Haematol. 2022 Feb 6. doi: 10.1111/bjh.18044. Online ahead of print. PMID: 35128632

Macrophage-based Cell Strategies: A Novel Approach in Immunotherapy.  Vinchi F. Hemasphere. 2022 Feb 4;6(2):e682. doi: 10.1097/HS9.0000000000000682. eCollection 2022 Feb. PMID: 35198857

Interferon α-induced SAMHD1 regulates human cultured megakaryocyte apoptosis and proplatelet formation.  Bhatlekar S, Jacob S, Tugolukova E, Manne BK, Kosaka Y, Loher P, O’Connell RM, Planelles V, Rondina MT, Rigoutsos I, Bray PF. Haematologica. 2022 Feb 1;107(2):558-561. doi: 10.3324/haematol.2021.279864. PMID: 34758609

Multiomic identification of factors associated with progression to cystic kidney disease in mice with nephron Ift88 disruption.  Hu C, Beebe K, Hernandez EJ, Lazaro-Guevara JM, Revelo MP, Huang Y, Maschek JA, Cox JE, Kohan DE. Am J Physiol Renal Physiol. 2022 Feb 1;322(2):F175-F192. doi: 10.1152/ajprenal.00409.2021. Epub 2021 Dec 20. PMID: 34927449

Tissue factor activity is increased in neutrophils from JAK2 V617F-mutated essential thrombocythemia and polycythemia vera patients.  Reeves BN, Kim SJ, Song J, Wilson KJ, Henderson MW, Key NS, Pawlinski R, Prchal JT. Am J Hematol. 2022 Feb 1;97(2):E37-E40. doi: 10.1002/ajh.26402. Epub 2021 Nov 14. PMID: 34748652

 

2022 January

Acute Hepatic Porphyrias: “Purple Flags”-Clinical Features That Should Prompt Specific Diagnostic Testing.  Anderson KE, Desnick RJ, Stewart MF, Ventura P, Bonkovsky HL. Am J Med Sci. 2022 Jan;363(1):1-10. doi: 10.1016/j.amjms.2021.09.009. Epub 2021 Oct 2. PMID: 34606756

Fetomaternal hemorrhage: Evidence from a multihospital healthcare system that up to 40% of severe cases are missed.  Carr NR, Henry E, Bahr TM, Ohls RK, Page JM, Ilstrup SJ, Christensen RD. Transfusion. 2022 Jan;62(1):60-70. doi: 10.1111/trf.16710. Epub 2021 Oct 21. PMID: 34674275

Reference intervals for end-tidal carbon monoxide of preterm neonates.  Pakdeeto S, Christensen TR, Bahr TM, Gerday E, Sheffield MJ, Christensen KS, Supapannachart S, Nuntnarumit P, Sukwiset S, Ohls RK, Christensen RD. J Perinatol. 2022 Jan;42(1):116-120. doi: 10.1038/s41372-021-01207-2. Epub 2021 Sep 23. PMID: 34556800

An Erythropoietin-Independent Mechanism of Erythrocytic Precursor Proliferation Underlies Hypoxia Tolerance in Sea Nomads.  Ilardo M, Dos Santos MCF, Grote Beverborg N, Rajan M, Said MA, Verweij N, Van Der Harst P, Van Der Meer P, Leibold EA. Front Physiol. 2022 Jan 27;12:760851. doi: 10.3389/fphys.2021.760851. eCollection 2021. PMID: 35177992

Palladium Nanoplate-Based IL-6 Receptor Antagonists Ameliorate Cancer-Related Anemia and Simultaneously Inhibit Cancer Progression.  Zhu J, Fu Q, Wang S, Ren L, Feng W, Wei S, Zhang Z, Xu Y, Ganz T, Liu S. Nano Lett. 2022 Jan 26;22(2):751-760. doi: 10.1021/acs.nanolett.1c04260. Epub 2022 Jan 14. PMID: 35030010

Evolution of host-microbe cell adherence by receptor domain shuffling.  Baker EP, Sayegh R, Kohler KM, Borman W, Goodfellow CK, Brush ER, Barber MF. Elife. 2022 Jan 25;11:e73330. doi: 10.7554/eLife.73330. PMID: 35076392

Erythroid overproduction of erythroferrone causes iron overload and developmental abnormalities in mice.  Coffey R, Jung G, Olivera JD, Karin G, Pereira RC, Nemeth E, Ganz T. Blood. 2022 Jan 20;139(3):439-451. doi: 10.1182/blood.2021014054. PMID: 34614145

Nucleated Red Blood Cell Counts of Neonates Born Emergently 1-4 h after a Maternal Cardiac Arrest.  Bahr TM, Henry E, O’Brien EA, Christensen RD. Neonatology. 2022 Jan 19:1-5. doi: 10.1159/000521043. Online ahead of print. PMID: 35045419

ABCB10 Loss Reduces CD4+ T Cell Activation and Memory Formation.  Sun W, Jia X, Liesa M, Tantin D, Ward DM. J Immunol. 2022 Jan 15;208(2):328-337. doi: 10.4049/jimmunol.2100514. Epub 2021 Dec 10. PMID: 34893527

A Randomized, Phase 3, Trial of Interferon-α versus Hydroxyurea in Polycythemia Vera and Essential Thrombocythemia.  Mascarenhas J, Kosiorek HE, Prchal JT, Rambaldi A, Berenzon D, Yacoub A, Harrison CN, McMullin MFF, Vannucchi AM, Ewing J, O’Connell CL, Kiladjian JJ, Mead AJ, Winton EF, Leibowitz DS, De Stefano V, Arcasoy MO, Kessler CM, Catchatourian R, Rondelli D, Silver RT, Bacigalupo A, Nagler A, Kremyanskaya M, Levine MF, Arango Ossa JE, McGovern EM, Sandy L, Salama ME, Najfeld V, Tripodi J, Farnoud N, Penson AV, Weinberg RS, Price L, Goldberg JD, Barbui T, Marchioli R, Tognoni G, Rampal RK, Mesa RA, Dueck AC, Hoffman R. Blood. 2022 Jan 10:blood.2021012743. doi: 10.1182/blood.2021012743. Online ahead of print. PMID: 35007321

Lysosomal iron recycling in mouse macrophages is dependent upon both reductases LcytB and Steap3.  Meng F, Fleming BA, Jia X, Rousek AA, Mulvey MA, Ward DM. Blood Adv. 2022 Jan 4:bloodadvances.2021005609. doi: 10.1182/bloodadvances.2021005609. Online ahead of print. PMID: 34982827

Sod1 integrates oxygen availability to redox regulate NADPH production and the thiol redoxome.  Montllor-Albalate C, Kim H, Thompson AE, Jonke AP, Torres MP, Reddi AR. Proc Natl Acad Sci U S A. 2022 Jan 4;119(1):e2023328119. doi: 10.1073/pnas.2023328119. PMID: 34969852

GFI1 Cooperates with IKZF1/IKAROS to Activate Gene Expression in T-cell Acute Lymphoblastic Leukemia.  Sun W, Guo J, McClellan D, Poeschla A, Bareyan D, Casey MJ, Cairns BR, Tantin D, Engel ME. Mol Cancer Res. 2022 Jan 3. doi: 10.1158/1541-7786.MCR-21-0352. Online ahead of print. PMID: 34980595

Dysregulation of the sensory and regulatory pathways controlling cellular iron metabolism in unilateral obstructive nephropathy.  Votava JA, Reese SR, Deck KM, Nizzi CP, Anderson SA, Djamali A, Eisenstein RS. Am J Physiol Renal Physiol. 2022 Jan 1;322(1):F89-F103. doi: 10.1152/ajprenal.00537.2020. Epub 2021 Nov 29. PMID: 34843656