Congratulations to CIHD Postdoctoral Core Trainee Allison Fisher and the Jodie Babitt lab for their recent publication
in Blood
Endothelial ZIP8 plays a minor role in BMP6 regulation by iron in mice
Abstract:
Iron-mediated induction of bone morphogenetic protein (BMP)6 expression by liver endothelial cells is essential for iron homeostasis regulation. We used multiple dietary and genetic mouse cohorts to demonstrate a minor functional role for the metal-ion transporter ZIP8 in regulating BMP6 expression under high-iron conditions.