2024 Publications
June 2024
Understanding the stability of a plastic-degrading Rieske iron oxidoreductase system. Beech JL, Maurya AK, Rodrigues da Silva R, Akpoto E, Asundi A, Fecko JA, Yennawar NH, Sarangi R, Tassone C, Weiss TM, DuBois JL.Protein Sci. 2024 Jun;33(6):e4997. doi: 10.1002/pro.4997.PMID: 38723110
Neonatal and Obstetrical Outcomes of Pregnancies Complicated by Alloimmunization. Bahr TM, Tweddell SM, Zalla JM, Dizon-Townson D, Ohls RK, Henry E, Ilstrup SJ, Kelley WE, Ling CY, Lindgren PC, O’Brien EA, Christensen RD.Pediatrics. 2024 Jun 1;153(6):e2023064604. doi: 10.1542/peds.2023-064604.PMID: 38784990
Iron Deficiency and Incident Heart Failure in Older Community-Dwelling Individuals. Sharma S, Katz R, Chaves PHM, Hoofnagle AN, Kizer JR, Bansal N, Ganz T, Ix JH.ESC Heart Fail. 2024 Jun;11(3):1435-1442. doi: 10.1002/ehf2.14724. Epub 2024 Feb 26.PMID: 38407565
SET domain containing 2 promotes megakaryocyte polyploidization and platelet generation through methylation of α-tubulin. Chen L, Liu J, Chen K, Su Y, Chen Y, Lei Y, Si J, Zhang J, Zhang Z, Zou W, Zhang X, Rondina MT, Wang QF, Li Y.J Thromb Haemost. 2024 Jun;22(6):1727-1741. doi: 10.1016/j.jtha.2024.03.010. Epub 2024 Mar 25.PMID: 38537781
Evaluation of EGFR and COX pathway inhibition in human colon organoids of serrated polyposis and other hereditary cancer syndromes. Kanth P, Hazel MW, Schell JC, Rutter J, Yao R, Mills AP, Delker DA.Fam Cancer. 2024 Apr 12. doi: 10.1007/s10689-024-00370-7. Online ahead of print.PMID: 38609520
May 2024
Low-Titer Type O Whole Blood for Transfusing Perinatal Patients after Acute Hemorrhage: A Case Series. Carr NR, Bahr TM, Ohls RK, Tweddell SM, Morris DS, Rees T, Ilstrup SJ, Kelley WE, Christensen RD. AJP Rep. 2024 May 3;14(2):e129-e132. doi: 10.1055/s-0044-1786712. eCollection 2024 Apr.PMID: 38707262
Oct4 redox sensitivity potentiates reprogramming and differentiation. Shen Z, Wu Y, Manna A, Yi C, Cairns BR, Evason KJ, Chandrasekharan MB, Tantin D. GenesDev. 2024 May 21;38(7-8):308-321. doi: 10.1101/gad.351411.123.PMID: 38719541
An age-progressive platelet differentiation path from hematopoietic stem cells causes exacerbated thrombosis. Poscablo DM, Worthington AK, Smith-Berdan S, Rommel MGE, Manso BA, Adili R, Mok L, Reggiardo RE, Cool T, Mogharrab R, Myers J, Dahmen S, Medina P, Beaudin AE, Boyer SW, Holinstat M, Jonsson VD, Forsberg EC.Cell. 2024 May 8:S0092-8674(24)00413-6. doi: 10.1016/j.cell.2024.04.018. Online ahead of print.PMID: 38749423
Neonatal NET-Inhibitory Factor inhibits macrophage extracellular trap formation. Bircher JS, Denorme F, Cody MJ, de Araujo CV, Petrey AC, Middleton EA, Campbell RA, Yost CC.Blood Adv. 2024 May 29:bloodadvances.2024013094. doi: 10.1182/bloodadvances.2024013094. Online ahead of print.
Molecular mechanism of choline and ethanolamine transport in humans. Ri K, Weng TH, Claveras Cabezudo A, Jösting W, Zhang Y, Bazzone A, Leong NCP, Welsch S, Doty RT, Gursu G, Lim TJY, Schmidt SL, Abkowitz JL, Hummer G, Wu D, Nguyen LN, Safarian S.Nature. 2024 May 22. doi: 10.1038/s41586-024-07444-7. Online ahead of print.PMID: 38778100
Microbe transmission from pet shop to lab-reared zebrafish reveals a pathogenic birnavirus. Rice MC, Janik AJ, Elde NC, Gagnon JA, Balla KM.PLoS Biol. 2024 May 30;22(5):e3002606. doi: 10.1371/journal.pbio.3002606. eCollection 2024 May.PMID: 38814944
GAGE-seq concurrently profiles multiscale 3D genome organization and gene expression in single cells. Zhou T, Zhang R, Jia D, Doty RT, Munday AD, Gao D, Xin L, Abkowitz JL, Duan Z, Ma J.NatGenet. 2024 May 14. doi: 10.1038/s41588-024-01745-3. Online ahead of print.PMID: 38744973
Dose-Adjusted EPOCH Plus Inotuzumab Ozogamicin in Adults With Relapsed or Refractory B-Cell ALL: A Phase 1 Dose-Escalation Trial. Kopmar NE, Quach K, Gooley TA, Martino CH, Cherian S, Percival MM, Halpern AB, GhiuzeliCM, Oehler VG, Abkowitz JL, Walter RB, Cassaday RD.JAMA Oncol. 2024 May 9:e240967. doi: 10.1001/jamaoncol.2024.0967. Online ahead of print.PMID: 38722664
Treatment of refractory/relapsed Diamond-Blackfan anaemia with eltrombopag. Duncan BB, Lotter JL, Superata J, Barranta ME, Machado T, Darden I, Venugopal S, Wu CO, Abkowitz JL, Dunbar CE, Young DJ.Br J Haematol. 2024 May;204(5):2077-2085. doi: 10.1111/bjh.19357. Epub 2024 Mar 10.PMID: 38462764
Phospholipid isotope tracing suggests β-catenin-driven suppression of phosphatidylcholine metabolism in hepatocellular carcinoma. VanSant-Webb C, Low HK, Kuramoto J, Stanley CE, Qiang H, Su AY, Ross AN, Cooper CG, Cox JE, Summers SA, Evason KJ, Ducker GS.Biochim Biophys Acta Mol Cell Biol Lipids. 2024 May 23;1869(6):159514. doi: 10.1016/j.bbalip.2024.159514. Online ahead of print.PMID: 38795827
Hyperferritinemia among very-low-birthweight infants in Thailand: a prospective cohort study. Laohajeeraphan C, Tantanate C, Christensen RD, Ngerncham S.J Perinatol. 2024 May;44(5):709-716. doi: 10.1038/s41372-023-01839-6. Epub 2023 Dec 7.PMID: 38062158
The phospholipids cardiolipin and phosphatidylethanolamine differentially regulate MDC biogenesis. Xiao T, English AM, Wilson ZN, Maschek JA, Cox JE, Hughes AL. J Cell Biol. 2024 May 6;223(5):e202302069. doi: 10.1083/jcb.202302069. Epub 2024 Mar 18.PMID: 38497895
The clinical management of porphyria cutanea tarda: An update. Sarkany RPE, Phillips JD.Liver Int. 2024 May 30. doi: 10.1111/liv.15980. Online ahead of print.PMID: 38813949
The mechanism of covalent inhibition of LAR phosphatase by illudalic acid. Hansen DT, Rueb NJ, Levinzon ND, Cheatham TE 3rd, Gaston R Jr, Tanvir Ahmed K, Osburn-Staker S, Cox JE, Dudley GB, Barrios AM.Bioorg Med Chem Lett. 2024 May 15;104:129740. doi: 10.1016/j.bmcl.2024.129740. Epub 2024 Apr 9.PMID: 38599294
Congenital erythropoietic porphyria. To-Figueras J, Erwin AL, Aguilera P, Millet O, Desnick RJ.Liver Int. 2024 May 8. doi: 10.1111/liv.15958. Online ahead of print.PMID: 38717058
April 2024
Novel germline JAK2R715T mutation causing PV-like erythrocytosis in 3 generations. Amelioration by Ropeg-Interferon. Song J, Lanikova L, Kim SJ, Papadopoulos N, Meznarich J, Constantinescu SN, ParsegovB, Prchal JF, Prchal JT.Am J Hematol. 2024 Apr 17. doi: 10.1002/ajh.27311. Online ahead of print.PMID: 38629639
Iron biology. Del Vecchio L, Girelli D, Vinchi F, Cozzolino M, Elliott S, Mark PB, Valenti L, Qian C, Guo Q, Qian ZM, Ciceri P, Locatelli F.Nephrol Dial Transplant. 2024 Apr 24:gfae095. doi: 10.1093/ndt/gfae095. Online ahead of print.PMID: 38658189
Utility of Blood Biomarkers to Predict Marrow Iron Stores in Children. Sharma S, Pereira RC, Nemeth E, Hanudel MR, Ix JH, Salusky IB, Ganz T.Clin J Am Soc Nephrol. 2024 Apr 30. doi: 10.2215/CJN.0000000000000469. Online ahead of print.PMID: 38687125
Diabetes and pancreatic cancer risk in a multiracial cohort. Conway RBN, Hudson AG, Munro H, Fu D, McClain DA, Blot WJ.Diabet Med. 2024 Apr;41(4):e15234. doi: 10.1111/dme.15234. Epub 2023 Oct 15.PMID: 37779225
Sedentary behavior in mice induces metabolic inflexibility by suppressing skeletal muscle pyruvate metabolism. Siripoksup P, Cao G, Cluntun AA, Maschek JA, Pearce Q, Brothwell MJ, Jeong MY, Eshima H, Ferrara PJ, Opurum PC, Mahmassani ZS, Peterlin AD, Watanabe S, Walsh MA, Taylor EB, Cox JE, Drummond MJ, Rutter J, Funai K.J Clin Invest. 2024 Apr 23;134(11):e167371. doi: 10.1172/JCI167371.PMID: 38652544
Anderson-Fabry disease management: role of the cardiologist. Pieroni M, Namdar M, Olivotto I, Desnick RJ.Eur Heart J. 2024 Apr 21;45(16):1395-1409. doi: 10.1093/eurheartj/ehae148.PMID: 38486361
A survey of iron supplementation, iron status surveillance, and erythropoiesis stimulating agent use in level III NICUs in the United States. Tuttle JJ, Bahr TM, Tweddell SM, Christensen RD, Ohls RK.J Perinatol. 2024 Apr 25. doi: 10.1038/s41372-024-01950-2. Online ahead of print.PMID: 38664494
Ubiquitin E3 Ligase FBXO9 Regulates Pluripotency by Targeting DPPA5 for Ubiquitylation and Degradation. Swenson SA, Dobish KK, Peters HC, Bea Winship C, Willow Hynes-Smith R, Caplan M, Wittorf KJ, Ghosal G, Buckley SM.Stem Cells. 2024 Apr 15;42(4):317-328. doi: 10.1093/stmcls/sxae004.PMID: 38227647
Epithelial cell states associated with kidney and allograft injury. Hinze C, Lovric S, Halloran PF, Barasch J, Schmidt-Ott KM.Nat Rev Nephrol. 2024 Apr 17. doi: 10.1038/s41581-024-00834-0. Online ahead of print.PMID: 38632381
March 2024
Endothelial ZIP8 plays a minor role in BMP6 regulation by iron in mice. Fisher AL, Phillips S, Wang CY, Paulo JA, Xiao X, Moschetta GA, Sridhar A, ManciasJD, Babitt JL.Blood. 2024 Mar 22:blood.2023023385. doi: 10.1182/blood.2023023385.
The alternative coproporphyrinogen III oxidase (CgoN) catalyzes the oxygen-independent conversion of coproporphyrinogen III into coproporphyrin III. Mingers T, Barthels S, Mass V, Acuña JMB, Biedendieck R, Cooke A, Dailey TA, Gerdes S, Blankenfeldt W, Dailey HA, Warren MJ, Jahn M, Jahn D.Front Microbiol. 2024 Mar 13;15:1378989. doi: 10.3389/fmicb.2024.1378989. eCollection 2024.PMID: 38544863
HJV mutations causing hemochromatosis: variable phenotypic expression in a pair of twins. Vadivelan A, Zhang S, Srole DN, Marcus EA, Neto GC, Nemeth E, Ganz T, De Oliveira S.Haematologica. 2024 Mar 7. doi: 10.3324/haematol.2023.284134. Online ahead of print.PMID: 38450514
Measurement of red cell, plasma and blood volume: Essential components of diagnostic and research studies of oxygen transport. Lichtman MA, Prchal JT.Blood Cells Mol Dis. 2024 Mar;105:102819. doi: 10.1016/j.bcmd.2023.102819. Epub 2023 Dec 7.PMID: 38101224
February 2024
Iron Deficiency and Incident Heart Failure in Older Community-Dwelling Individuals. Sharma S, Katz R, Chaves PHM, Hoofnagle AN, Kizer JR, Bansal N, Ganz T, Ix JH.ESC Heart Fail. 2024 Feb 26. doi: 10.1002/ehf2.14724. Online ahead of print.PMID: 38407565
Iron restriction in sickle cell disease: When less is more. Castro OL, De Franceschi L, Ganz T, Kanter J, Kato GJ, Pasricha SR, Rivella S, Wood JC.Am J Hematol. 2024 Feb 23. doi: 10.1002/ajh.27267. Online ahead of print.PMID: 38400590
Finding a fountain of youth in the blood. Portier I, Andrianova I, Campbell RA.J Thromb Haemost. 2024 Feb;22(2):311-314. doi: 10.1016/j.jtha.2023.10.024. Epub 2023 Nov 7.PMID: 37940049
Reciprocal stabilization of coagulation factor XIII-A and -B subunits is a determinant of plasma FXIII concentration. Byrnes JR, Lee T, Sharaby S, Campbell RA, Dobson DA, Holle LA, Luo M, Kangro K, Homeister JW, Aleman MM, Luyendyk JP, Kerlin BA, Dumond JB, Wolberg AS.Blood. 2024 Feb 1;143(5):444-455. doi: 10.1182/blood.2023022042.PMID: 37883802
Inhibition of the skeletal muscle Lands cycle ameliorates weakness induced by physical inactivity. Shahtout JL, Eshima H, Ferrara PJ, Maschek JA, Cox JE, Drummond MJ, Funai K.J Cachexia Sarcopenia Muscle. 2024 Feb;15(1):319-330. doi: 10.1002/jcsm.13406. Epub 2023 Dec 20.PMID: 38123161
A shift between mineral and nonmineral sources of iron and sulfur causes proteome-wide changes in Methanosarcina barkeri. Fausset H, Spietz RL, Cox S, Cooper G, Spurzem S, Tokmina-Lukaszewska M, DuBois J, Broderick JB, Shepard EM, Boyd ES, Bothner B.Microbiol Spectr. 2024 Feb 6;12(2):e0041823. doi: 10.1128/spectrum.00418-23. Epub 2024 Jan 5.PMID: 38179920 Free PMC article.
Homologous acetone carboxylases select Fe(II) or Mn(II) as the catalytic cofactor. Shisler KA, Kincannon WM, Mattice JR, Larson J, Valaydon-Pillay A, Mus F, Flusche T, Kumar Nath A, Stoian SA, Raugei S, Bothner B, DuBois JL, Peters JW.mBio. 2024 Feb 14;15(2):e0298723. doi: 10.1128/mbio.02987-23. Epub 2023 Dec 21.PMID: 38126751
Durable CD4+ T cell immunity: cherchez la stem. Hughes EP, Syage AR, Tantin D. Trends Immunol. 2024 Feb 21:S1471-4906(24)00004-8. doi: 10.1016/j.it.2024.01.004. Online ahead of print.PMID: 38388231
OCA-B/Pou2af1 is sufficient to promote CD4+ T cell memory and prospectively identifies memory precursors. Sun W, Hughes EP, Kim H, Perovanovic J, Charley KR, Perkins B, Du J, Ibarra A, Syage AR, Hale JS, Williams MA, Tantin D.Proc Natl Acad Sci U S A. 2024 Feb 27;121(9):e2309153121. doi: 10.1073/pnas.2309153121. Epub 2024 Feb 22.PMID: 38386711
January 2024
Novel frontiers in gene therapy: In vivo gene editing. Vinchi F. Hemasphere. 2024 Jan 28;8(1):e25. doi: 10.1002/hem3.25. eCollection 2024 Jan.PMID: 38434529
Measurement of red cell, plasma, and blood volume: A perspective. Prchal JT, Lichtman MA.Am J Hematol. 2024 Jan;99(1):9-11. doi: 10.1002/ajh.27158. Epub 2023 Nov 15.PMID: 37966977
Ubiquitin E3 ligase FBXO9 regulates pluripotency by targeting DPPA5 for ubiquitylation and degradation. Swenson SA, Dobish KK, Peters HC, Winship CB, Hynes-Smith RW, Caplan M, Wittorf KJ, Ghosal G, Buckley SM.Stem Cells. 2024 Jan 16:sxae004. doi: 10.1093/stmcls/sxae004. Online ahead of print.PMID: 38227647
Recurrent viral capture of cellular phosphodiesterases that antagonize OAS-RNase L. Goldstein SA, Elde NC.Proc Natl Acad Sci U S A. 2024 Jan 30;121(5):e2312691121. doi: 10.1073/pnas.2312691121. Epub 2024 Jan 26.PMID: 38277437
Immunothrombosis in neurovascular disease. Denorme F, Ajanel A, Campbell RA.Res Pract Thromb Haemost. 2023 Dec 20;8(1):102298. doi: 10.1016/j.rpth.2023.102298. eCollection 2024 Jan.PMID: 38292352
Mitofusin-2 Regulates Platelet Mitochondria and Function. Jacob S, Kosaka Y, Bhatlekar S, Denorme F, Benzon H, Moody A, Moody V, Tugolukova EA, Hull G, Kishimoto N, Manne BK, Guo L, Souvenir R, Seliger BJ, Eustes AS, Hoerger K, Tolley ND, Fatahian AN, Boudina S, Christiani DC, Wei Y, Ju C, Campbell RA, Rondina MT, Abel ED, Bray PF, Weyrich AS, Rowley JW.Circ Res. 2024 Jan 19;134(2):143-161. doi: 10.1161/CIRCRESAHA.123.322914. Epub 2023 Dec 29.PMID: 38156445
Erythrokinetic mechanism(s) causing the “late anemia” of hemolytic disease of the fetus and newborn. Christensen RD, Bahr TM, Ohls RK, Ilstrup SJ, Moise KJ Jr, Lopriore E, Meznarich JA.J Perinatol. 2024 Jan 12. doi: 10.1038/s41372-024-01872-z. Online ahead of print.PMID: 38216678
Lactate administration improves laboratory parameters in murine models of iron overload. Liu W, Wu Y, Wei H, Ma J, Feng W, Yang Q, Zhang S, Ganz T, Liu S.Blood. 2024 Jan 9:blood.2023021695. doi: 10.1182/blood.2023021695. Online ahead of print.PMID: 38194678
Exploring the relationship between hyperlactatemia and anemia. Zhang S, Liu W, Ganz T, Liu S.Trends Endocrinol Metab. 2024 Jan 6:S1043-2760(23)00251-5. doi: 10.1016/j.tem.2023.12.006. Online ahead of print.PMID: 38185594
Placental ferroportin protein abundance is associated with neonatal erythropoietic activity and iron status in newborns at high risk for iron deficiency and anemia. Barad A, Guillet R, Pressman EK, Katzman PJ, Ganz T, Nemeth E, O’Brien KO.Am J Clin Nutr. 2024 Jan;119(1):76-86. doi: 10.1016/j.ajcnut.2023.10.022. Epub 2023 Oct 27.PMID: 37890671