Welcome

NIDDK-Sponsored Center for Iron & Hematology Disorders at The University of Utah School of Medicine

The Center for Iron and Hematology Disorders (CIHD) at the University of Utah School of Medicine consists of three scientific core facilities which include the Mutation Generation & Detection Core, the Metabolomics Core, and the Iron & Heme Core. In addition to these Cores, there is an Enrichment Program, Internal and External Advisory Committees, and a Pilot and Feasibility program for the Center for Iron and Hematology Disorders. These cores offer many different services to a large majority of members within the CIHD as well as The University of Utah. To contact Core directors, find out services provided, and the rates of these services, click on the respective page. To find out upcoming events these Cores and programs will be providing, click on Events Calendar.

News

Call for Pilot Grant Applications

Our NIDDK Center for Iron and Heme Disorders (CIHD) will fund three pilot grants of $25,000 each (total costs) for this next fiscal year. We funded three proposals in year 1 of our CIHD grant and will follow the same format as last year for the second round of pilot awards.

The grants will be awarded competitively and are designed to support research projects from internal and external CIHD members that utilize our CIHD Cores and advance the mission of our program; non-malignant hematology with an emphasis on iron and heme. Our intent is also to: 1) Support junior faculty members or established investigators launching new research directions that meet our mission objectives; 2) Promote collaborative and interdisciplinary research initiatives between CIHD members. Instructions for submitting an application can be found under Pilot & Feasibility at our website: cihd.cores.utah.edu

 Applications are due Friday September 1, 2017. Awards will be made by October 1 and funding will commence shortly thereafter.

Those who are not yet members of the CIHD can apply for membership through our web page and be eligible for pilot grant funding. We hope you consider submitting an application by September 1. If you have questions, please contact Dr. Dennis Winge at dennis.winge@hsc.utah.edu.

CRISPR-RNP Transfection Workshop: July 27-28

Presented by the Mutation Generation and Detection Core, The Center for Iron and Heme Disorders, and The Center for Clinical and Translational Science

This Workshop will present two days of morning informational seminars dicussing the use of CRISPR-RNP technology in cell culture cells from design, optimization, and delivery. Along with a Keynote address by Dr. Dana Carroll on the ethical and societal issues of the use of CRISPR technologies. Informational seminars will be open to all researchers.

The afternoon wet lab portion will allow researchers to gain hands experience with the production of CRISPR-RNP complexes and their Nucleofection into cell culture cells. If you are interested in registering for the wet lab portion, please contact the Mutation Generation and Detection Core at mutrus@genetics.utah.edu or 801-585-0662.

 

Thursday, July 27

Eccles Auditorium, EIHG

09:00-10:30AM Dr. Greg Alberts Background on Genome Editing

10:30-10:45AM Coffee Break

11:00-12:00PM Dr. Greg Alberts Issues in CRISPR-Cas Editing

12:00-1:00PM Break for Lunch

1:00-5:00PM Wet Lab Day 1 MGD Core Room 7470 EIHG Production of CRISPR-RNP

Friday, July 28

Eccles Auditorium, EIHG

09:00-10:00AM Michael Collingwood “Mitigating risk of off-target effects when using CRISPR genome editing”

10:00-10:10AM Coffee Break

10:15-11:15AM Dr. Dana Carroll “Ethical and Societal Issues Surrounding Genome Editing”

11:30-12:30PM Break for Lunch

12:30-4:30PM Wet Lab Day 2 MGD Core Room 7470 EIHG Analysis of Nucleofected cells for

Sponsored by Lonza and Integrated DNA Technologies

Congratulations!

Congratulations to Andrew Melber who successfully defended his Ph.D. thesis in February 2017. “Role of Nfu1 and Bol3 in iron-sulfer cluster transfer to mitochondrial clients.” Andy completed his research in the laboratory  of Dennis Winge. Best wishes in his subsequent scientific endeavors.