Career

We are seeking a Lab Specialist to join our HSC Cell Imaging Core. The ideal candidate will have a strong passion for microscopy and expertise in a research program coordinating role. Key responsibilities include maintaining microscopy equipment, organizing daily core activities, and ensuring effective communication with our users. For more details, please use this link https://utah.peopleadmin.com/postings/165605.

If you have any additional questions about this position, please don’t hesitate to contact Xiang Wang (Xiang.wang@cores.utah.edu).

Post/Doctoral position available at the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda MD, for a young researcher interested in joining a young and dynamic research group in mammalian iron metabolism, iron sulfur cofactors, iron related neurodegeneration, iron sulfur dependent viral replication, RNA protein interactions and systems biology analysis of iron regulation.

Terms: 24 months, with yearly extensions possible after initial contract. The NIH is dedicated to building an inclusive and diverse community in its training and employment programs.

DHHS, NIH, and NICHD are Equal Employment Opportunity Employers

For further information, contact: rouault@mail.nih.gov.

Postdoctoral position is available in the Krause laboratory at Yale (krauselab.net). Our lab focuses on how hematopoietic stem and progenitor cells function to maintain hematopoiesis in health, and the molecular mechanisms that dysregulate these cells in leukemia and other disease states. We use in vitro and in vivo cell and molecular approaches to reveal mechanisms of cell fate determination and transformation. The Krauselab specifically and Yale in general is a highly collaborative environment. We are looking for a candidate who enjoys both working independently and also as part of a team.

Eligibility: US citizen or Green Card holder.

Qualifications: PhD, MD, or both with a strong track record of training and independent research in Cell and Molecular Biology, Genetics or related transdisciplinary fields. Experience in cell culture and molecular biology as well as excellent communication and interpersonal skills are required.

Candidates should have a strong publication track record with first author publications in English journals.

Interested candidates should send a CV with names of references to diane.krause@yale.edu.

Please visit our lab website at krauselab for more information about our ongoing projects and recent publications. We look forward to welcoming an enthusiastic and dedicated postdoctoral fellow to contribute to our exciting research endeavors at Yale University.

The University of Maryland Baltimore, School of Medicine’s, interdisciplinary Center for Blood Oxygen Transport & Hemostasis includes a team of physicians, biochemists, and engineers and will help answer fundamental, challenging questions related to blood function in health and disease.

This fellowship is funded by an NIH post-doctoral training grant and will focus on mechanisms that drive sickle cell disease (SCD) pulmonary hypertension (PH). Accumulation of pulmonary vascular macrophage iron is a new and unique finding observed in SCD, suggesting that erythrophagocytosis mediated iron overload is a pathological driver of progressive pulmonary vascular disease. This is in striking contrast to idiopathic pulmonary arterial hypertension (iPAH), which is exacerbated by iron depletion states and may be improved in some cases by iron administration. The study of macrophage processing of sickled red blood cells, macrophage migration to the pulmonary vasculature and iron driven pulmonary vascular remodeling will be the primary focus of this post-doctoral fellowship. Secondarily, mechanisms such as inflammation and complement activation will also be studied as processes that exacerbate PH. Both murine models and patient samples will be studies to define proof-of-concept for experimental therapeutics that slow the progression of pulmonary vascular complications in SCD.

The fellow will assist in research studies to advance knowledge in a training-based setting under the direction of Dr. Paul Buehler, a federally funded pharmacologist and toxicologist with specialization in hematotoxicology. The position requires an ability to carry out general laboratory techniques (e.g., spectrophotometry, ELISAs, Western blotting, flow cytometry, histopathology, and microscopy). Evaluation of RBC deformability, oxygen equilibrium, preparation for microscopy (light and EM), capability to assess RBC morphological changes consistent with disease states will be taught. Further, a knowledge and/or desire to expand expertise in techniques that evaluate tissue oxygenation and perfusion (e.g., MRI, EPR, PET, Phosphorescence Quenching, Laser Doppler Flowmetry) is critical to this position’s goals.

Minimum Education: Recent graduate applicants with a PhD or applicants that are expected to graduate from a Bioengineering, Physiology, or related discipline PhD program and are required to be a green card holder or US citizen. The candidate will be expected to possess strong communication and independent writing skills.

Interested candidates should email their CV and Research Statement to PBuehler@som.umaryland.edu.

Salary: In accordance with NIH guidelines (NIH 0–3-year experience level)

A full-time Lab Technician position is available in the Rutter Lab ( http://rutter.biochem.utah.edu/ ) in the Department of Biochemistry at the University of Utah. We are looking for a highly motivated individual who is interested in working as part of a multidisciplinary and dynamic team to perform cutting-edge research towards revealing the human protein-metabolite interactome for a better understanding of human metabolism, health, and disease. Previous hands-on, laboratory research experience is preferred, but not required. Duties include SDS – PAGE , Western blot, UV-Vis spectrophotometry, High-pressure or fastpressure liquid chromatography, recombinant protein expression and purification, and other protein biochemistry techniques. Responsibilities will be modified as the technician gains lab experience. This position is ideal for a candidate wishing to gain hands-on laboratory experience before applying for graduate school, medical school, or both.

Responsibilities Performs laboratory research under the direction of a supervisor. The successful applicant will be trained and perform SDS – PAGE , Western blot, UV-Vis spectrophotometry, fast-pressure liquid chromatography, recombinant protein expression and purification, and other protein biochemistry techniques. Maintains detailed electronic laboratory notebook. Analyzes, presents, and discusses data. Attends and participates in lab meetings and interest groups. Maintains lab inventory and databases. Contributes to general laboratory maintenance and general reagent production as needed. The ideal candidate will have excellent focus and attention to detail, organizational skills in recordkeeping, multitasking, prioritizing responsibilities, time management, knowing when to ask for help, and an ability to interact with all levels of staff. This job description is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities, and qualifications required of employees assigned to the job.

Minimum Qualifications Bachelor’s degree in biology, chemistry, or other scientific disciplines in a related field or equivalency (one year of education can be substituted for two years of related work experience) required; knowledge of complex laboratory techniques, equipment, terminology, materials and substances. Skilled in the use of laboratory equipment, ability to create and analyze statistical calculations and prepare reports required; and demonstrated human relations and effective communication skills also required. OSHA training and certification in animal care and use or the willingness to complete the certification may be required by some departments. Applicants must demonstrate the potential ability to perform the essential functions of the job as outlined in the position description.

Preferences Bachelor’s degree in biochemistry, molecular biology, chemistry, or related subject. Demonstrated skill in written and verbal communication. Demonstrated ability to work independently and ask for guidance when needed. Previous hands-on research experience is preferred, but not required.

A full-time Lab Technician position is available in the Rutter Lab in the Department of Biochemistry at the University of Utah. We are looking for a highly motivated individual who is interested in working as part of a multi-disciplinary and dynamic team to perform cutting-edge research towards revealing the human protein metabolite interactome for a better understanding of human metabolism, health, and disease. Previous hands-on, laboratory research experience is preferred, but not required.